 Home > Encyclopedia > 2-Pyridinethiol 1-oxide

2-Pyridinethiol 1-oxide

2-Pyridinethiol 1-oxide structure

CAS No:
1121-31-9
Formula:
C5H5NOS
Chemical Name:
2-Pyridinethiol 1-oxide
Synonyms:
MercaptypyridineNoxideanhydrous;N-Hydroxy-2-thiopyridone;pyridine-2-thiol N-oxide;2-MERCAPTOPYRIDINE-N-OXIDE 99%;2-MERCAPTOPYRIDINE N-OXIDE SODIUM SALT ANHYDROUS, 98%;PYRIDINETHIOLOXIDE;Pyrithione (and/or unspecified salts);2-MERCAPTOPYRIDINE-N-OXIDE 90% ,PYRITHIONE 90%
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

off-white powder

ChEBI: Pyrithione is a pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. It has a role as an ionophore. It is a pyridinethione and a monohydroxypyridine. It is a tautomer of a pyridine-2-thiol N-oxide.

2-MercaptopyridineN-oxide forms complexes on reaction with palladium chloride. It inhibits NADH-fumarate reductase purified fromTrypanosoma cruzi. It is precursor toO-acyl thiohydroxamates. It ligates to metals to form biologically active complexes.

2-Pyridinethiol 1-oxide Basic Attributes

Molecular Weight：

127.16

Exact Mass：

127.16

BRN：

906983

EC Number：

214-329-4

TSCA：

TSCA listed

Color/Form：

Off-white to beige or yellow to yellow-greenish or grayish-green

HScode：

29333990

Characteristics

PSA：

64.26000

XLogP3：

-0.90

Appearance：

Off-white to beige or yellow to yellow-greenish or grayish-green Powder, Crystals, and/or Chunks

Density：

1.255 (estimate)

Melting Point：

69-72 °C (lit.)

Boiling Point：

350.2±15.0 °C(Predicted)

Flash Point：

165.6±20.4 °C

Refractive Index：

1.5480 (estimate)

Water Solubility：

soluble in tris-hydrochloric acid.

Storage Conditions：

Refrigerator

Vapor Pressure：

0mmHg at 25°C

PKA：

5.40±0.50(Predicted)

Critical Temperature & Pressure：

Refrigerator

Safety Information

Transport codes：

2811

wgk germany：

hazard class code：

Xi,Xn

safety instructions：

26-36-24/25-36/37-22

RTECS Number：

UT8999000

Marks：

Xi,Xn

Stability/Shelf Life：

Stable. Incompatible with strong bases, strong oxidizing agents.

Precautionary statement(s)：

P261-P301 + P310-P305 + P351 + P338

Hazard Statements：

36/37/38-22-63-20/21/22

RIDADR：

2811

2-Pyridinethiol 1-oxide Use and Manufacturing

Widely used in the preparation of various pyridinethione derivative products

2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

Precursor toO-acyl thiohydroxamates. Ligates to metals to form biologically active complexes.

Recommended Suppliers of 2-Pyridinethiol 1-oxide

LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Most Professional Factory Supply High Qulity 2-Pyridinethiol 1-oxide CAS 1121-31-9

CAS No.: 1121-31-9

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

2-Pyridinethiol 1-oxide

CAS No.: 1121-31-9

Content: 99.00%

Inquiry