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Home > Encyclopedia > N-Carbobenzyloxy-L-alanine

N-Carbobenzyloxy-L-alanine

N-Carbobenzyloxy-L-alanine structure

N-Carbobenzyloxy-L-alanine 

structure
  • CAS No:

    1142-20-7

  • Formula:

    C11H13NO4

  • Chemical Name:

    N-Carbobenzyloxy-L-alanine

  • Synonyms:

    N-CBZ-L-ALANINE;N-CBZ-L-ALANINE-OH;N-CARBOBENZYLOXY-L-ALANINE;N-ALPHA-BENZYLOXYCARBONYL-L-ALANINE;N-ALPHA-CARBOBENZOXY-L-ALANINE;N-ALPHA-CBZ-L-ALANINE;N-BENZYLOXYCARBONYL-L-ALANINE;Z-L-ALANINE extrapure

  • Categories:

    Pharmaceutical Intermediates  >  Gastrointestinal Agents

Description

white powder

N-Carbobenzyloxy-L-alanine Basic Attributes

223.23

223.23

2056164

214-532-8

DTXSID40150674

White

29242990

Characteristics

75.6

1.4

White Powder

1.2446 (rough estimate)

84-87 °C

364.51°C (rough estimate)

209.1±26.8 °C

-14.5 ° (C=2, AcOH)

0-6°C

7.05E-08mmHg at 25°C

-15 º (c=2, AcOH 24 ºC)

4.00±0.10(Predicted)

Sealed in dry,Room Temperature

Safety Information

IRRITANT

NONH for all modes of transport

3

Xn

22-24/25-36-26

Xn

Stable under normal temperatures and pressures.

20/21/22-36/37/38

|Warning|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 5 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Cbz-Ala

N-Carbobenzyloxy-L-alanine Use and Manufacturing

Used in biochemical reagents and peptide synthesis.


N-Benzyloxycarbonyl-L-alanine is an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

Computed Properties

Molecular Weight:223.22
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:223.08445790
Monoisotopic Mass:223.08445790
Topological Polar Surface Area:75.6
Heavy Atom Count:16
Complexity:248
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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