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Home > Encyclopedia > Testosterone, isobutyrate

Testosterone, isobutyrate

Testosterone, isobutyrate structure

Testosterone, isobutyrate 

structure
  • CAS No:

    1169-49-9

  • Formula:

    C23H34O3

  • Chemical Name:

    Testosterone, isobutyrate

  • Synonyms:

    Androst-4-en-3-one,17-(2-methyl-1-oxopropoxy)-,(17β)-;Testosterone,isobutyrate;Isobutyric acid,ester with testosterone;(17β)-17-(2-Methyl-1-oxopropoxy)androst-4-en-3-one;Perandren M;Testosterone 17-isobutyrate;Testosterone 2-methylpropionate;17β-(Isobutyroxy)androst-4-en-3-one;3-Oxoandrost-4-en-17β-yl isobutyrate;Agovirin-Depot;Testocryst;Testosterone 2-methylpropanoate

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Testosterone Isobutyrate is an four-carbon ester form of Testosterone. The number of ester carbon atoms correlate with the half-life of the prodrug. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels. In addition, this agent promotes the maintenance of male sex characteristics and is indicated for testosterone replacement in hypogonadal males. (NCI04)

Testosterone, isobutyrate Basic Attributes

358.51400

358.51

214-622-7

H0KNQ242J5

DTXSID70151573

C1248

Characteristics

43.37000

5.08610

1.09 g/cm3

134-136 °C

462.6ºC at 760 mmHg

198.8ºC

1.533

Safety Information

P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H302+H312+H332

|Warning|H302+H312+H332 (50%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Perandren M

Computed Properties

Molecular Weight:358.5
XLogP3:4.9
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:358.25079494
Monoisotopic Mass:358.25079494
Topological Polar Surface Area:43.4
Heavy Atom Count:26
Complexity:648
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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