Glycol monoethyl ether acetate
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Glycol monoethyl ether acetate
structure -
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CAS No:
111-15-9
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Formula:
C6H12O3
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Chemical Name:
Glycol monoethyl ether acetate
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Synonyms:
Ethanol,2-ethoxy-,1-acetate;Ethanol,2-ethoxy-,acetate;β-Ethoxyethyl acetate;2-Ethoxyethyl acetate;Ethylene glycol ethyl ether acetate;Ethylene glycol monoethyl ether acetate;Glycol monoethyl ether acetate;Poly-Solv EE acetate;Cellosolve acetate;O-Ethylglycol acetate;Oxitol acetate;2-Ethoxyethanol acetate;Ethyl cellosolve acetate;Ethylene glycol monoethyl ether monoacetate;1-Acetoxy-2-ethoxyethane;Ethylene glycol acetate monoethyl ether;NSC 8658;2-Ethyloxyethyl acetate;Ethyl glycol acetate
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CAS No:
Characteristics
35.5
0.24
Ethylene glycol monoethyl ether acetate appears as a clear colorless liquid with a pleasant odor. Flash point of 120°F. Less dense than water. Vapors are heavier than air.
0.975 g/cm3 @ Temp: 20 °C
-61.7 °C
156 °C
135 °F
1.401
H2O: 230 g/L (20 ºC)
Flammables area
2 mm Hg ( 20 °C)
4.6 (vs air)
Oral-Rat LD50: 2700 mg/kg; Oral-Mouse LD50: 1910 mg/kg
In case of fire, high temperature, oxidant is more flammable; burning produces irritating smoke
1.7-10%(V)
MILD ESTER-LIKE ODOR BECOMES OBJECTIONABLE IN HIGH CONCN ...
... A BITTER ACID TASTE
Safety Information
III
3
UN 1172 3/PG 3
1
60-61-20/21/22-10
53-45
KK8225000
T
Treasury is ventilated, low temperature and dry; stored separately from oxidant
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases, nitrates.
P201-P280-P308 + P313
H226-H302 + H312 + H332-H360FD
Glycol monoethyl ether acetate Use and Manufacturing
1. From the reaction of ethylene glycol monoethyl ether and acetic anhydride, mix acetic anhydride and concentrated sulfuric acid. After heating to 130°C, slowly add ethylene glycol monoethyl ether dropwise. The reaction temperature is maintained at 130-135°C. Add flow for 1-2h, and reflux temperature is 140℃. After cooling, it is neutralized with sodium carbonate to pH=7-8, and then dried with industrial anhydrous potassium carbonate. Filter out the desiccant for crude fractionation and collect the distillate at 150-160°C. Then fractional distillation, collect the 155.5-156.5 ℃ fraction is the finished product. It can also be obtained by reacting ethylene glycol monoethyl ether and acetic acid with concentrated sulfuric acid and refluxing in benzene. Ethylene glycol monoethyl ether reacts with acetic acid under the catalysis of cationic resin to continuously remove the generated water, and then distill the finished product. The conversion rate of acetic acid in this method is 94.5%, and the selectivity of the product is 98.5%. 2. 2-Ethoxyacetic acid and ethanol reaction method. 3. Ethyl acetate and ethoxyethanol transesterification method. 4. Acetic acid and ethoxyethanol reaction method. 5. Reaction method of ethylene oxide and ethyl acetate.
Ethylene glycol ether acetate (CAC) is an ester solvent with excellent performance.
Computed Properties
Molecular Weight:132.16
XLogP3:0.3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:132.078644241
Monoisotopic Mass:132.078644241
Topological Polar Surface Area:35.5
Heavy Atom Count:9
Complexity:80.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Price Analysis
- Data: 2026-10-13
- Price: 11075.00Yuan/mt
- Change: 0
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