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Glucosamine hydrochloride

Glucosamine hydrochloride structure

CAS No:
66-84-2
Formula:
C6H13NO5.ClH
Chemical Name:
Glucosamine hydrochloride
Synonyms:
D-Glucose,2-amino-2-deoxy-,hydrochloride (1:1);D-Glucose,2-amino-2-deoxy-,hydrochloride;Glucosamine hydrochloride;D-Glucosamine hydrochloride;D-(+)-Glucosamine hydrochloride;2-Amino-2-deoxy-D-glucose hydrochloride;Chitosamine hydrochloride;Cosamin;2-Deoxy-2-amino-D-glucose hydrochloride;D-Glucosamine chloride;NSC 234443;NSC 758;Koyo Glucosamine MG;Glucosamine FM;2002-25-7;3615-52-9;34673-29-5;66573-21-5;151799-45-0;214046-22-7;581076-92-8;619328-18-6;885318-70-7;1029131-60-9;1334320-70-5;2378838-02-7;2411172-99-9
Categories:
Cosmetic Ingredient > Antistatic

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Description

Glucosamine (hydrochloride) is a natural product.

Glucosamine hydrochloride Basic Attributes

Molecular Weight：

215.63

Exact Mass：

215.056046

BRN：

4157370

EC Number：

200-638-1

NSC Number：

283301

DSSTox ID：

DTXSID5037236

HScode：

29329985

Characteristics

PSA：

124.01000

XLogP3：

-1.91010

Appearance：

crystalline

Melting Point：

217.857 °C

Boiling Point：

449.9ºC at 760 mmHg

Flash Point：

225.9ºC

Water Solubility：

H2O: soluble

Storage Conditions：

Store at RT.

Specific rotation：

72.5 º (c=2, H2O, 5hrs.)

Safety Information

wgk germany：

hazard class code：

21-36/38-46-62-63

safety instructions：

24/25-53-36/37-26-25

RTECS Number：

LZ6665000

Marks：

F,Xi,Xn

Storage features：

NONH for all modes of transport

Hazard note：

Highly Flammable

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents. Combustible.

GHS Classification：

Not Classified

Drug Information

Drug Indication：

Primary osteoarthritis

Glucosamine hydrochloride Use and Manufacturing

Uses

Novel application of glucosamine to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.

Use Classification：

Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:215.63
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:215.0560502
Monoisotopic Mass:215.0560502
Topological Polar Surface Area:116
Heavy Atom Count:13
Complexity:155
Undefined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Material

Potassium hydroxide

2-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1)

Citric acid

Drug Function and Efficacy

It can stimulate chondrocytes to produce proteoglycans with normal polymer structures, inhibit enzymes that damage cartilage, such as collagenase and phospholipase A2, and prevent the production of superoxide free radicals that damage cells, thereby delaying or reversing the pathological process of osteoarthritis and the progression of the disease, improving joint movement, and relieving pain.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Glucosamine Hydrochloride Tablets
Ingredients	Main ingredients: The main ingredient of this product is glucosamine hydrochloride.
Indication	Not yet clear.
Specifications	0.24 g
Manufacturer	Sichuan Xinsidun Pharmaceutial Co., Ltd.

Glucosamine Hydrochloride Capsules
Ingredients	Each capsule of this product contains 0.75 grams of glucosamine hydrochloride, and the auxiliary material is magnesium stearate.
Indication	1. This product can increase the absorption of tetracycline drugs in the gastrointestinal tract and reduce the absorption of oral penicillin or chloramphenicol. 2. Patients taking non-steroidal anti-inflammatory drugs at the same time may need to reduce the dosage of this product, or reduce the dosage of non-steroidal anti-inflammatory drugs. 3. This product may interact with diuretics. When taking the two drugs at the same time, the dosage of diuretics may need to be increased. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a physician or pharmacist for details.
Specifications	0.75g*20s

Jiuzhentang Glucosamine Chondroitin Sulfate and Calcium Capsules
Specifications	0.5g/tablet

See More Related Drugs

Registered Holders

Harmony PharmaTech (Nanjing) Co., Ltd.

China
Active
Zhejiang Zhoushan Putuo Xinxing Pharmaceutical Co., Ltd.

China
Active
Zhejiang Qianyuan Haili Sheng Pharmaceutical Co., Ltd.

China
Active

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Guide of Glucosamine hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Material
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

Glucosamine hydrochloride

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