Metadoxine
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Metadoxine
structure -
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CAS No:
74536-44-0
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Formula:
C8H11NO3.C5H7NO3
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Chemical Name:
Metadoxine
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Synonyms:
L-Proline,5-oxo-,compd. with 5-hydroxy-6-methyl-3,4-pyridinedimethanol (1:1);3,4-Pyridinedimethanol,5-hydroxy-6-methyl-,compd. with 5-oxo-L-proline (1:1);Metadoxine;Metadoxil;Metasin;Alcoliv
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CAS No:
Description
Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.
Metadoxine Basic Attributes
298.295
298.116486
277-913-8
EJQ7M98H5J
A - Alimentary tract and metabolism
2936250000
Drug Information
Substances interfering with the metabolism of ethyl alcohol, causing unpleasant side effects thought to discourage the drinking of alcoholic beverages. Alcohol deterrents are used in the treatment of alcoholism. (See all compounds classified as Alcohol Deterrents.)
Metadoxil
Metadoxine Use and Manufacturing
Metadoxine can be used for treating patients for liver functional disorders in performing stomatologic interventions and in treatment of acute and chronic alcoholism
Computed Properties
Molecular Weight:298.29
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:298.11648630
Monoisotopic Mass:298.11648630
Topological Polar Surface Area:140
Heavy Atom Count:21
Complexity:297
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Improve liver function damage caused by long-term drinking, resist hepatocyte lipid peroxidation, and reduce fat accumulation in hepatocytes of animals with chronic alcoholism
Registered Holders
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Shandong Qidu Pharmaceutical Co., Ltd.
Active
China
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Zhejiang Zhenyuan Pharmaceutical Co., Ltd.
Active
China
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