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Tripotassium citrate monohydrate

pharmaceutical raw materials
Tripotassium citrate monohydrate structure

Tripotassium citrate monohydrate 

structure
  • CAS No:

    6100-05-6

  • Formula:

    C6H8O7.H2O.3K

  • Chemical Name:

    Tripotassium citrate monohydrate

  • Synonyms:

    1,2,3-Propanetricarboxylic acid,2-hydroxy-,potassium salt,hydrate (1:3:1);Citric acid,tripotassium salt,monohydrate;1,2,3-Propanetricarboxylic acid,2-hydroxy-,tripotassium salt,monohydrate;Tripotassium citrate monohydrate;209968-03-6

  • Categories:

    Organic Chemistry  >  Organometallic Compounds

Description

Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia and a derivative of citric acid. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects[1][2][3][4].

Tripotassium citrate monohydrate Basic Attributes

324.41

323.905212

231-905-0

760107

2918150000

Characteristics

142

-5.31690

Granular

1.98

275 °C (dec.)(lit.)

309.6ºC at 760 mmHg

155.2ºC

soluble in water and glycerol.Practically insoluble in alcohol. soluble in water and glycerol. Insoluble in alcohol;H2O: 1 M at 20 °C, clear, colorless

Store at RT.

Safety Information

NONH for all modes of transport

1

22-35

26-36/37/39-45-24/25

F,T,C,Xi

Stable. Incompatible with strong oxidizing agents.

Tripotassium citrate monohydrate Use and Manufacturing

As a food additive, food-grade potassium citrate can be used to adjust acidity and the source of potassium nutrition; it is used in the pharmaceutical industry for hypokalemia and potassium deficiency and alkalization of Chemicalbook urine. It helps to reduce the acidity of urine and has treatment Kidney disease and gout; it can also be made into high-efficiency compound fertilizers, and can also be used in papermaking, gilding and other industries.

Computed Properties

Molecular Weight:231.22
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:230.99070907
Monoisotopic Mass:230.99070907
Topological Polar Surface Area:132
Heavy Atom Count:14
Formal Charge:1
Complexity:227
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Downstream Products

Drug Function and Efficacy

Alkalinizing agent used to prevent kidney stones and manage urinary pH; also serves as a source of potassium

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Jungbunzlauer Ladenburg GmbH

    Germany Germany
    Active
  • Dr. Paul Lohmann GmbH & Co.KGaA

    Japan Japan
    Active
  • ARCHER DANIELS MIDLAND (CAMBODIA) CO., LTD.

    Kampuchea (Cambodia ) Kampuchea (Cambodia )
    Inactive

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