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Home > Encyclopedia > 4-Amino-2-hydroxybutanoic acid

4-Amino-2-hydroxybutanoic acid

4-Amino-2-hydroxybutanoic acid structure

4-Amino-2-hydroxybutanoic acid 

structure
  • CAS No:

    13477-53-7

  • Formula:

    C4H9NO3

  • Chemical Name:

    4-Amino-2-hydroxybutanoic acid

  • Synonyms:

    Butanoic acid,4-amino-2-hydroxy-;Butyric acid,4-amino-2-hydroxy-;4-Amino-2-hydroxybutanoic acid;HABA;2-Hydroxy-γ-aminobutyric acid;4-Amino-2-hydroxybutyric acid;γ-Amino-α-hydroxybutyric acid;DL-4-Amino-2-hydroxybutanoic acid;(RS)-2-Hydroxy-γ-aminobutyric acid;DL-4-Amino-2-hydroxybutyric acid;(RS)-2-Hydroxy-GABA;3938-83-8

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

4-Amino-2-hydroxybutanoic acid Basic Attributes

119.12

119.12

1308068-626-2

2922509090

Characteristics

83.6

-1.10

1.312±0.06 g/cm3(Predicted)

191-192 °C @ Solvent: Ethanol

361.8±27.0 °C(Predicted)

172.6±23.7 °C

1.511

Drug Information

4-amino-2-hydroxybutyric acid

4-Amino-2-hydroxybutanoic acid Use and Manufacturing

Methods of Manufacturing

Using γ-aminobutyric acid as the raw material, firstly protect the amino group, then carry out α-bromination, and then convert the bromine into acetoxy group, and finally hydrolyze to remove the protecting group, and resolve to obtain the product.

Uses

Intermediate of amikacin (type S).

Computed Properties

Molecular Weight:119.12
XLogP3:-3.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:119.058243149
Monoisotopic Mass:119.058243149
Topological Polar Surface Area:83.6
Heavy Atom Count:8
Complexity:83.4
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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