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Benproperine phosphate

Benproperine phosphate structure

CAS No:
19428-14-9
Formula:
C21H27NO.H3O4P
Chemical Name:
Benproperine phosphate
Synonyms:
Piperidine,1-[1-methyl-2-[2-(phenylmethyl)phenoxy]ethyl]-,phosphate (1:1);Piperidine,1-[1-methyl-2-[(α-phenyl-o-tolyl)oxy]ethyl]-,phosphate (1:1);Pirexyl;1-(2-Benzylphenoxy)-2-piperidinopropane phosphate;1-[2-(2-Benzylphenoxy)-1-methylethyl]piperidine monophosphate;ASA 158-5;Blascorid;Benproperine phosphate;1-[2-(2-Benzylphenoxy)-1-methylethyl]piperidinium dihydrogen phosphate
Categories:
Active Pharmaceutical Ingredients > Respiratory Drugs

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Description

Off-White Solid

Benproperine phosphate Basic Attributes

Molecular Weight：

407.44

Exact Mass：

407.186157

EC Number：

243-050-0

Characteristics

PSA：

90.2

XLogP3：

3.53990

Appearance：

powder

Melting Point：

150-152 °C

Boiling Point：

433ºC at 760mmHg

Flash Point：

126.8ºC

Vapor Pressure：

1.06E-07mmHg at 25°C

Toxicity：

LD50 orally in mice: 1431 mg/kg (Tellini, De Fina)

Benproperine phosphate Use and Manufacturing

An antitussive.Used for irritating dry cough. cough medicine

Material

Morpholine

Drug Function and Efficacy

This product is a non-addictive antitussive drug that can inhibit the cough center, inhibit the pulmonary vagus nerve reflex caused by lung and pleural stretch receptors, and relax bronchial smooth muscles. That is, it has both central and peripheral antitussive mechanisms.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Benproperine Phosphate Capsules
Ingredients	The main ingredient of this product is benproperine phosphate. Its chemical name is 1-[2-(2-benzylphenoxy)-1-methylethyl]piperidine phosphate.
Indication	Not yet clear.
Specifications	20mg (in terms of C21H27NO)

Benproperine Phosphate Capsules
Ingredients	The main ingredient of this product is benproperine phosphate. Its chemical name is 1-[2-(2-benzylphenoxy)-1-methylethyl]piperidine phosphate.
Indication	Not yet clear.
Specifications	20mg (in terms of C21H27NO)
Manufacturer	China Resources Zizhu Pharmaceutical Co., Ltd.

Benproperine Phosphate Capsules
Ingredients	The main ingredient of this product is benproperine phosphate. Its chemical name is 1-[2-(2-benzylphenoxy)-1-methylethyl]piperidine phosphate.
Indication	Not yet clear.
Specifications	26.4 mg (equivalent to 20 mg of benproperine)
Manufacturer	Guangdong Hengcheng Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Shanxi Shuangyan Pharmaceutical Co., Ltd.

China
Active
Suzhou NO.5 Pharmaceutical FACTORY Co., Ltd.

China
Active
Shanghai Yurui BIOTECHNOLOGY (Anyang) Pharmaceutical Co., Ltd.

China
Active

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CAS No.: 19428-14-9

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