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Home > Encyclopedia > Sodium oleate

Sodium oleate

pharmaceutical raw materials
Sodium oleate structure

Sodium oleate 

structure
  • CAS No:

    143-19-1

  • Formula:

    C18H34O2.Na

  • Chemical Name:

    Sodium oleate

  • Synonyms:

    9-Octadecenoic acid (9Z)-,sodium salt (1:1);Oleic acid,sodium salt;9-Octadecenoic acid (Z)-,sodium salt;9-Octadecenoic acid (9Z)-,sodium salt;Eunatrol;Olate Flakes;Sodium oleate;Pionin D 951P;NPS Red Oil Soap;Nonsoul ON 1;Lunac SO 90L;Nonsoul ON-A;Pionin A 5;Edenor OL 72MY,sodium salt;Ligaphob NT 90

  • Categories:

    Cosmetic Ingredient  >  Viscosity Controlling

Description

White powder; slight tallowlike odor. Soluble in water with partial decom- position; soluble in alcohol. Combustible. Light tan solid with a slight tallow-like odor. Sinks and mixes slowly with water.


Oleic acid, [sodium salt] is a light tan solid with a slight tallow-like odor. Sinks and mixes slowly with water. (USCG, 1999)|Liquid


Oleic acid, [sodium salt] is a light tan solid with a slight tallow-like odor. Sinks and mixes slowly with water. (USCG, 1999)|Sodium oleate is an organic molecular entity.

Sodium oleate Basic Attributes

304.44

304.237823

205-591-0

399SL044HN

DTXSID7021077

WHITE CRYSTALS OR YELLOW AMORPHOUS GRANULES|WHITE POWDER

29161500

Characteristics

40.1

4.77380

White to slightly yellow Powder

0.9 g/cm3

232-235 °C

360°C at 760 mmHg

270.099ºC

soluble H2O, partially decomposes; soluble alcohol

−20°C

LD50 ivn-mus: 152 mg/kg RPOBAR 2,327,70

SLIGHT TALLOW-LIKE ODOR

IN AQ SOLN IT IS ALKALINE... BUT NOT IN ALCOHOL SOLN

Water soluble. Gives basic aqueous solution.

Hydrocarbons, Aliphatic Unsaturated

Salts, basic, such as OLEIC ACID, [SODIUM SALT], are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Safety Information

NONH for all modes of transport

1

22-24/25-25-24

RK1200000

Stable. Incompatible with strong oxidizing agents.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Implantation or injectable dosage form new animal drugs. Specifications and conditions of use are provided for /oleate sodium solution/.

Dust mask and gloves (USCG, 1999)|... /NIOSH approved respirator/ and gloves.

SLIGHT WHEN EXPOSED TO HEAT OR FLAME

Water, foam, dry chemical, carbon dioxide.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Inhalation of dust causes irritation of nose and throat, coughing, and sneezing. Ingestion causes mild irritation of mouth. Contact with eyes causes irritation.

Toxicity

PROLONGED IMPAIRMENT OF THE PLASMA-PROTEIN BINDING OF PHENYTOIN IN THE RAT AFTER A SINGLE DOSE OF SODIUM OLEATE.

Drug Information

MEDICATION (VET): Sodium oleate is available for parenteral injection /in horses/ to stimulate invasion or infiltration of tissues by cellular blood components. The infiltrated cells differentiate into fibrous and/or fibrocartilagenous tissue. Sodium oleate is indicated in treatment of splints and microfractures of the cannon bone such as bucked shins. ... Sodium oleate (50 mg) will induce inflammation, swelling, and tenderness following parenteral administration in the affected region; it will cover a surface area of 15 sq cm.|MEDICATION (VET): OSTEUM (BRAND OF SODIUM OLEATE FORMULATION), SOLN 50 MG/ML VETERINARY, FOR USE IN HORSES ONLY. OSTEUM IS STERILE SOLN FOR PARENTERAL INJECTION... OSTEUM IS RECOMMENDED FOR STIMULATION OF FIBROUS & FIBROCARTILAGENOUS TISSUE. /OSTEUM/

Caution must be exercised in use of sodium oleate within 30 days following injection of a local corticosteroid /in horses/; severe tissue reactions have been known to occur. ... Horses intended for human food must not be injected with sodium oleate.

2= SLIGHTLY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 5-15 G/KG, BETWEEN 1 PINT & 1 QT FOR 70 KG PERSON (150 LB). /SOAPS/

GENERALLY CONTAINS SMALL QUANTITIES OF SODIUM SALTS OF STEARIC, ETC, ACIDS.

Inhalation of dust causes irritation of nose and throat, coughing, and sneezing. Ingestion causes mild irritation of mouth. Contact with eyes causes irritation. (USCG, 1999)

INHALATION: move to fresh air. INGESTION: give large amount of water. EYES: flush with copious quantities of tap water. SKIN: flush with water. (USCG, 1999)

BY INTRAUTERINE INJECTION (AS IN SOME CRIMINAL ABORTIONS), SOAPS CAUSE HEMOLYSIS, EMBOLI, HYPERPYREXIA, SHOCK, RENAL DAMAGE, & OFTEN PROMPT DEATH. /SOAPS/

osteum

Sodium oleate Use and Manufacturing

Methods of Manufacturing

SODIUM...SALTS OF FATTY ACID, PREPARED FROM EDIBLE FATS.|ACTION OF ALCOHOLIC SODIUM HYDROXIDE ON OLEIC ACID.

Uses

preparation of Turkey red oil, soft soap and other oleates; in polishing Compounds; waterproofing textiles, oiling wool; manufacture of driers; thickening lubricating oils.Pharmaceutic aid (solvent).The barium salt in rodent extermination.


Emulsifier used for washing out residual monomer after the reaction is completed.


Laundry and dishwashing products

Production

500,000 - 1,000,000 lb|(1984) 1.71X10+8 g /Oleic acid salts/|99,000 kg in 1990 /Oleic acid salts/

Nonmetallic mineral product manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other nonmetallic mineral product manufacturing.|9-Octadecenoic acid (9Z)-, sodium salt (1:1): ACTIVE|MIGRATES TO FOOD FROM PACKAGING MATERIALS.

EPA Safer Chemical Functional Use Classes -> Surfactants|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|Cosmetics -> Cleansing; Emulsifying; Surfactant; Viscosity controlling

Computed Properties

Molecular Weight:304.4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:15
Exact Mass:304.23782457
Monoisotopic Mass:304.23782457
Topological Polar Surface Area:40.1
Heavy Atom Count:21
Complexity:239
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Downstream Products

Drug Function and Efficacy

Emulsifier

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Unokang (Beijing) Pharmaceutical Technology Service Co., Ltd.

    China China
    Active
  • Sichuan Kelun-Doosan Biotechnology Company Limited.

    China China
    Active
  • Xi'an Li Bang Pharmaceutical Co., Ltd.

    China China
    Active

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