Cefmenoxime hydrochloride
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Cefmenoxime hydrochloride
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CAS No:
75738-58-8
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Formula:
C16H17N9O5S3.1/2ClH
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Chemical Name:
Cefmenoxime hydrochloride
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Synonyms:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,hydrochloride (2:1),(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,hydrochloride (2:1),[6R-[6α,7β(Z)]]-;Cefmenoxime hemihydrochloride;Cefmenoxime hydrochloride;Bestcall;Tacef;Abbott 50192;Cemix;Cefmax;Bestron
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CAS No:
Description
Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
A cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Characteristics
539
0.04020
Oral-rat LD50: > 20000 mg/kg; Oral-Mouse LD50: 17540 mg/kg
Thermal decomposition releases toxic nitrogen oxides, sulfur oxides, hydrogen chloride fumes
Safety Information
Ⅲ
2811
6.1
The warehouse is low-temperature, ventilated and dry
|Danger|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P285, P302+P352, P304+P341, P321, P333+P313, P342+P311, P363, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
Abbott 50192
Cefmenoxime hydrochloride Use and Manufacturing
antibacterial
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:1059.6
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:28
Rotatable Bond Count:16
Exact Mass:1058.0796341
Monoisotopic Mass:1058.0796341
Topological Polar Surface Area:539
Heavy Atom Count:67
Complexity:890
Undefined Atom Stereocenter Count:4
Undefined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Unspecified
Registered Holders
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China UNION Chempharma (SUZHOU) Co., Ltd.
Active
China
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CSPC Zhongnuo PHARMACEUTICAL(Shijiazhuang) Co., Ltd.
Active
China
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Shanghai SPH New ASIA Pharmaceutical Co., Ltd.
Active
China
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