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Flusilazole

Flusilazole structure

CAS No:
85509-19-9
Formula:
C16H15F2N3Si
Chemical Name:
Flusilazole
Synonyms:
1H-1,2,4-Triazole,1-[[bis(4-fluorophenyl)methylsilyl]methyl]-;1-[[Bis(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole;DPX-H 6573;Flusilazole;Flusilazol;Punch;Punch (pesticide);Nustar;DPD 78710F;DPX-N 6573;Punch 40EC;Lyric;Olymp;Olymp 10EX;Sanction;Benocarp;Punch Bis;Capitan;Cane Strike;Cursor;Bis(4-fluorophenyl)methyl(1H-1,2,4-triazole-1-ylmethyl)silane;Genie;Genie (fungicide);Genie 25;96827-34-8;1135441-07-4
Categories:
Agrochemicals > Fungicides

Description

Brown-red viscous liquid

Solid

Flusilazole is an organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops. It has a role as a xenobiotic, an environmental contaminant, an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of monofluorobenzenes, a member of triazoles, an organosilicon compound, a conazole fungicide and a triazole fungicide.

Flusilazole Basic Attributes

Molecular Weight：

315.39

Exact Mass：

315.39

EC Number：

617-717-5

UNII：

F3WG2VVD87

DSSTox ID：

DTXSID3024235

HScode：

2933990015

Characteristics

PSA：

30.7

XLogP3：

3.70

Appearance：

Solid

Density：

1.2±0.1 g/cm3

Melting Point：

54 °C

Boiling Point：

393.00 °C

Flash Point：

192°C

Refractive Index：

1.563

Water Solubility：

900 mg l -1 (pH 1.1), 50 mg l -1 (pH 5.7), 45 mg l -1 (pH 7.8) at 25 °C

Storage Conditions：

0-6°C

Vapor Pressure：

3.9 x l0 -8 Pa (25 °C)

Toxicity：

LD50 in male, female rats (mg/kg): 1110, 674 orally; in rabbits >2000 dermally (Fort, Moberg)

Safety Information

Transport codes：

UN 2588

wgk germany：

hazard class code：

61-22-40-51/53

safety instructions：

53-45-61

RTECS Number：

XZ4105000

Marks：

T;N,N,T

Stability/Shelf Life：

Stable at normal temperatures and storage conditions.

Precautionary statement(s)：

P201-P273-P281-P308 + P313

Hazard Statements：

H302-H351-H360D-H411

GHS Classification：

|Danger|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P264, P270, P273, P281, P301+P312, P308+P313, P330, P391, P405, and P501|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|Aggregated GHS information provided by 210 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Mobility：

1.66e+03 L/kg

Drug Information

MeSH：

Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc. (See all compounds classified as Fungicides, Industrial.)

MeSH Entry Terms：

DPX-H6573

Flusilazole Use and Manufacturing

Methods of Manufacturing

Chloromethyldichlorosilane reacts with fluorobenzene and butyllithium at low temperature to produce bis(4-fluorophenyl)methylchloromethylsilane, which is then reacted with 1, 2, 4- in a polar solvent Sodium triazole reaction to produce fluosilazole.

Uses

Agricultural fungicide.

Use Classification：

Agrochemicals -> Fungicides|Fungicides

Agrochemical：

Flusilazole has known environmental transformation products that include bis(4-fluorophenyl)(methyl)silanol.

Computed Properties

Molecular Weight:315.39
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:315.10033035
Monoisotopic Mass:315.10033035
Topological Polar Surface Area:30.7
Heavy Atom Count:22
Complexity:333
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Butyllithium

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Flusilazole

CAS No.: 85509-19-9

Content: 99.00%

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Flusilazole Systemic Triazole Fungicide for Effective Crop Disease Management

CAS No.: 85509-19-9

Grade: Industrial Grade

Content: 95%

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