 Home > Encyclopedia > Diclazuril

Diclazuril

Diclazuril structure

CAS No:
101831-37-2
Formula:
C17H9Cl3N4O2
Chemical Name:
Diclazuril
Synonyms:
Benzeneacetonitrile,2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-;2,6-Dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitrile;R 64433;Diclazuril;Clinacox;P 64433;Vecoxan;Nuoqiu;2-(4-Chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile
Categories:
Active Pharmaceutical Ingredients > Antiparasitic Drugs

Description

Off-White SolidDiclazuril (molecular formula: C17H9Cl3N4O2, Trade name: Vecoxan) belongs to a kind of coccidiostat and potent antiprotozoal agents. It is mainly used for the treatment, control, prevention and improvements of Coccidal infections. It alleviates the symptoms of the patients by interrupting the life cycle of the parasites. It induces the morphological changes and attenuates the mitochondrial transmembrane potential in meroites. It can prevent congenital toxoplasmosis and have antic

2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile is a nitrile.|Diclazuril is a coccidiostat.

Diclazuril Basic Attributes

Molecular Weight：

407.64

Exact Mass：

407.64

EC Number：

1806241-263-5

NSC Number：

759642

DSSTox ID：

DTXSID4046787

HScode：

29336990

Characteristics

PSA：

85.6

XLogP3：

4.1

Appearance：

yellowish or white powder

Density：

1.56±0.1 g/cm3(Predicted)

Melting Point：

290.5°

Refractive Index：

1.701

Storage Conditions：

0-6°C

Safety Information

Packing level：

Ⅲ

Transport codes：

3077

wgk germany：

hazard class code：

safety instructions：

24/25

RTECS Number：

CY1697600

Stability/Shelf Life：

Stable at normal temperatures and pressures.

Precautionary statement(s)：

P273, P391, P501

Hazard Statements：

H400

GHS Classification：

|Warning|H361 (79.55%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]|P201, P202, P260, P273, P281, P308+P313, P314, P391, P405, and P501|Aggregated GHS information provided by 45 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH：

Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals. (See all compounds classified as Coccidiostats.)

MeSH Entry Terms：

2,6-dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitrile

Diclazuril Use and Manufacturing

Uses

antiprotozoal

Use Classification：

Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients|Veterinary Drug -> ANTIPROTOZOAL_AGENT; -> JECFA Functional Classes|Pharmaceuticals -> Animal Drugs -> Approved in Taiwan

Food Additive Classes：

Veterinary Drug -> ANTIPROTOZOAL_AGENT;

Computed Properties

Molecular Weight:407.6
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:405.979109
Monoisotopic Mass:405.979109
Topological Polar Surface Area:85.6
Heavy Atom Count:26
Complexity:629
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Diclazuril

Arshine Group Co., Ltd. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of cosmetic additives,Veterinary APIs,Feed additives,medical and pharmaceutical packaging materials,pharmaceutical equipment,Natural Nutrition Ingredients,intermediates,Food Additives,Medical Devices,Human APIs

Diclazuril 101831-37-2 Not less than 96%

CAS No.: 101831-37-2

Grade: Pharmaceutical Grade

Content: 96.3%

Inquiry
Xi'an Horlden Bio-Tech Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide,KY19382,5-deazaflavin,Dihexa,Urolithin A

Diclazuril 101831-37-2 Antiparasitic Agents Veterinary Medicine

CAS No.: 101831-37-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

HOT SALE Diclazuril 99% high quality see COA KANBEI

CAS No.: 101831-37-2

Grade: Industrial Grade

Content: 99%

Inquiry
First Chems Co., LTD Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of Titanium dioxide,npk,pvc,sles,labsa,mdi,tdi,Ethylene glycol,p-xylene,mtbe,styrene,Ethyl alcohol,Anthracite (coke),Citric acid,carbinol,toluene,Acetic acid,Dichloroethane,Phenol

Supply Veterinary Medicine Raw Material CAS 101831-37-2 Diclazuril Powder with good price

Unit Price: $100-110 /KG FOB

CAS No.: 101831-37-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shandong Qinshi Biotechnology Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Inosine pranobex,Sodium Ceftiofur,Ceftiofur hydrochloride,ceftiofur

Diclazuril

CAS No.: 101831-37-2

Grade: Chemical Grade

Content: 96%

Inquiry