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Tirofiban hydrochloride

Tirofiban hydrochloride structure

CAS No:
142373-60-2
Formula:
C22H36N2O5S.ClH
Chemical Name:
Tirofiban hydrochloride
Synonyms:
L-Tyrosine,N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-,hydrochloride (1:1);L-Tyrosine,N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-,monohydrochloride;MK 383;N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine hydrochloride;Tirofiban hydrochloride;L 700462;Aggrastat
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Description

Tirofiban was launched as Aggrastat in Switzerland and the US for patients with unstable angina or non-Q-wave myocardial infarction to prevent cardiac ischemic events. Tirofiban is synthesized from (S)-tyrosine by a fourstep process. Tirofiban is a novel highly potent antiplatelet agent that inhibits the interaction of fibrinogen with GPⅡb/Ⅲa, an activated platelet membrane-bound glycoprotein complex. It prevents arterial thrombus formation in a dosedependent manner. Clinical efficacy was

Tirofiban hydrochloride Basic Attributes

Molecular Weight：

495.07

Exact Mass：

494.221741

Characteristics

PSA：

122.34000

XLogP3：

5.48870

Melting Point：

223-225ºC

Boiling Point：

611.7ºC at 760mmHg

Flash Point：

323.7ºC

Tirofiban hydrochloride Use and Manufacturing

Aggrastat (Millot Laboratories, France).

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Tirofiban hydrochloride

CAS No.: 142373-60-2

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TIROFIBAN HYDROCHLORIDE MONOHYDRATE 99% see COA kanbei

CAS No.: 142373-60-2

Grade: Industrial Grade

Content: 99%

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