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Tolterodine tartrate

Tolterodine tartrate structure

CAS No:
124937-52-6
Formula:
C22H31NO.C4H6O6
Chemical Name:
Tolterodine tartrate
Synonyms:
Phenol,2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-,(2R,3R)-2,3-dihydroxybutanedioate (1:1);Phenol,2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-,(R)-,[R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt);Phenol,2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-,(2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt);Detrusitol;Tolterodine tartrate;PNU 200583E;Detrol;Tolterodinium (+)-(2R,3R)-hydrogen tartrate (1:1);(R)-Tolterodine L-tartrate;(R)-(+)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine L-tartrate;Tolterodine L-tartrate;(R)-Tolterodine tartrate;Tolterodine tartaric acid;Terol
Categories:
Biochemical Engineering > Inhibitors

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Description

White-to-Off-White Crystalline Powder

Tolterodine tartrate Basic Attributes

Molecular Weight：

475.57

Exact Mass：

475.256989

EC Number：

1592732-453-0

HScode：

29222990

Characteristics

PSA：

139

XLogP3：

3.21880

Appearance：

White-to-Off-White Crystalline Powder

Density：

1.003 g/cm3

Melting Point：

216 °C

Boiling Point：

243.3°C at 760 mmHg

Flash Point：

192.1ºC

Storage Conditions：

Store at +4°C

Vapor Pressure：

1.97E-08mmHg at 25°C

Toxicity：

LD50 i.v. in male mice: 10-20 mg/kg (Jnsson)

Specific rotation：

54625 +36.0°

Safety Information

Transport codes：

UN 2811 6.1 / PGIII

hazard class code：

36/37/38

safety instructions：

26-37/39

Marks：

Precautionary statement(s)：

Missing Phrase - N15.00950417-P280

Hazard Statements：

H301-H361

Tolterodine tartrate Use and Manufacturing

Tolterodine (tartrate) is a competitive antagonist of muscarinic (M) receptors (Ki = 1.4, 2.7, 3.6, 3.1, and 2.2 nM for M1 through M5, respectively). Antagonists of muscarinic receptors, including tolterodine, are effective in treating overactive bladder symptoms.[Cayman Chemical]

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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Registered Holders

MAITHRI LABORATORIES PRIVATE LTD

United States
Active
EMCURE PHARMACEUTICALS LTD

United States
Active
APITORIA PHARMA PRIVATE LTD

United States
Active

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