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Home > Encyclopedia > Kasugamycin hydrochloride

Kasugamycin hydrochloride

pharmaceutical raw materials
Kasugamycin hydrochloride structure

Kasugamycin hydrochloride 

structure
  • CAS No:

    19408-46-9

  • Formula:

    C14H25N3O9.ClH

  • Chemical Name:

    Kasugamycin hydrochloride

  • Synonyms:

    D-chiro-Inositol,3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-,hydrochloride (1:1);Kasugamycin,monohydrochloride;D-chiro-Inositol,3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-,monohydrochloride;Kasumin;Kasugamycin hydrochloride;11014-57-6;12609-82-4;39080-40-5;1135443-65-0

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1][2].

Kasugamycin hydrochloride Basic Attributes

415.82

415.135742

234-260-3

Characteristics

218.81000

log Kow = -5.75 (est)

white to off-white

1.97g/cm3

202-204 °C (decomp)

628.2ºC at 760mmHg

333.7ºC

1.738

H2O: soluble

2-8°C

<1.3X10-4 mm Hg at 25 °C

Oral-Rat LD50: 22000 mg/kg; Oral-Mouse LD50: 20500 mg/kg

Combustion produces toxic nitrogen oxides and hydrogen chloride gas

Safety Information

NONH for all modes of transport

2

22-24/25-26

NM7521800

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Toxicity

practically nontoxic

Kasugamycin hydrochloride Use and Manufacturing

antifungal

Drug Function and Efficacy

Unspecified

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • North China Pharmaceutical Huasheng Co., Ltd.

    China China
    Active

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