Avermectin B1a
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Avermectin B1a
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CAS No:
65195-55-3
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Formula:
C48H72O14
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Chemical Name:
Avermectin B1a
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Synonyms:
Avermectin A1a,5-O-demethyl-;Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran],avermectin A1a deriv.;5-O-Demethylavermectin A1a;Antibiotic C 076B1a;Avermectin B1a;L 676863;Abamectin B1a;Abamectin component B1a;355401-08-0;2036285-79-5;2355205-03-5
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CAS No:
Description
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
Characteristics
170.06000
6.51
1.2±0.1 g/cm3
157-162ºC
940.9±65.0 °C at 760 mmHg
268.1±27.8 °C
1.571
Oral-rat LD20: 10 mg/kg; Oral-Mouse LD50: 19 mg/kg
Flammable; burning produces irritating fumes
Avermectin B1a Use and Manufacturing
Avermectin B1a is the major component (>80%) of a commercially available anthelmintic used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 25-position. In vitro and in vivo studies have shown that this analogue is the more potent analogue in the commercial product.
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