Diammonium hydrogen phosphate

132.06

132.029999

231-987-8

10LGE70FSU

0217

DTXSID6029705

White crystals|Crystals or crystalline powder

31053000

85.4

-0.28080

White Powder

1.619 g/cm³

155 °C (decomp)

158ºC at 760 mmHg

1.53

H2O: 58 g/ 100mL (10 ºC)

Store at RT.

Reference value: Oral-rat LD50: 17000 mg/kg; Abdominal-rat LDL0: 1000 mg/kg

Heating produces toxic nitrogen oxides, phosphorus oxides and ammonia fumes

Odorless

Saline, cooling taste

pH about 8

Heat of solution: 42 Btu/lb = 23 cal/g|Decomposes into ammonia and monoammonium phosphate at about 70 °C. Unstable at room temperature and exhibits an ammonium vapor pressure in the solid form and in solution.|Gradually loses about 8% ammonia on exposure to air.

UN 3465 6.1 / PGIII

1

36/37/38-20/21/22-50

26-36-61-37/39

TB9385000

Xi,Xn,N

Warehouse ventilated, low temperature and dry

Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.

P261, P264, P271, P280, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H312

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

Incompatible with strong oxidizers, strong bases. Contact with air causes this chemical to produce anhydrous ammonia fumes.

The food additive diammonium phosphate may be safely used in ruminant feed in accordance with the following prescribed conditions: (a) The food additive is the product resulting from the neutralization of feeding-phosphoric-acid or defluorinated wet-process phosphoric acid with anhydrous ammonia. It contains not less than 106.25% equivalent crude protein (nitrogen X 6.25) and 20% phosphorus. It contains not more than the following: 1 part fluorine to 100 parts phosphorus; 75 ppm arsenic (as As); 30 ppm heavy metals, as lead (Pb). (b) It is used in ruminant feeds as a source of phosphorus and nitrogen in an amt that supplies not more than 2% of equivalent crude protein in the total daily ration.|Ammonium phosphate (mono-, and dibasic) used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.|Substance added directly to human food affirmed as generally recognized as safe (GRAS).

WHO; Diseases Caused by Phosphorus and Its Toxic Compounds; Early Detection of Occupational Diseases pg 53-62 (1986). Review of diseases and health related effects resulting from exposure to phosphorus or phosphorus cmpd.

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

|Warning|H312 (32.79%): Harmful in contact with skin [Warning Acute toxicity, dermal]|P261, P264, P271, P280, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 632 companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

/NIOSH certified respirator/, protective gloves, and goggles. When diammonium phosphate is stored in closed area, self-contained breathing apparatus is required to protect ammonia fumes.

Noncombustible.

Use extinguishing agents suitable for surrounding fire. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors, or shows any sign of deforming), withdraw immediately to a secure position.

Poisonous gases including ammonia, phosphorus oxides, and nitrogen oxides are produced in fire.

Stop discharge if possible. Keep people away. Avoid contact with solid and dust. Isolate and remove discharged material. Notify health and pollution control agencies.

SRP: In bulk storage or manufacturing situations where combustible dusts can collect in sufficient concentrations to give rise to an explosion/deflagration, reasonable precautions shall be taken to reduce or eliminate the hazard. Efforts shall be made to control or eliminate the five elements necessary to initiate a dust explosion. These include combustible dust (fuel), ignition source (heat), oxygen in air (oxidizer), and dispersion of dust particles in sufficient quantity and concentration as well as confinement of the dust cloud. General guidance in these efforts can be found in OSHA's "Combustible Dust in Industry; Preventing and Mitigating the Effects of Fire and Explosions", which list measures to control dusts, eliminate ignition sources, and limit the effects of explosions.|SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Dust irritating to eyes, and throat. Solid irritating to skin and eyes.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

Separated from strong oxidants, strong bases and strong acids. Keep in a well-ventilated room.

Evaporation at 20 °C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

The substance is irritating to the eyes.

Use local exhaust.

Protective gloves.

Wear safety spectacles.

moderately toxic

This paper summarizes data on the factors involved in addiction and dependence to cigarettes. Nicotine has been intensively studied by the tobacco industry, for instance for its addictive effect at the lowest possible rates. The addition of diammonium phosphate and urea produces an alcalinization of the pH of cigarette smoke, and promotes the absorption and the trans-membrane passage of nicotine. The taste, the smell of smoke, and the visual aspect of the pack of cigarettes are also sensory components that promote addiction. Finally, menthol, sugar, cocoa and liquorice added to cigarettes also play a role in dependence and addiction to cigarettes by, for instance, making an anesthetic effect on the airways.

LD50 Rabbit dermal >7950 mg/kg bw|LD50 Rat oral 6500 mg/kg bw

/AQUATIC SPECIES/ Acute toxicity to five freshwater fishes and a scud was determined in static tests. 96 hr LC50 ranged from 40 mg/L for scuds to 1500 mg/L for fingerling fish. In salmon and trout, yolk-sac fry were more susceptible than swim-up fry.|/AQUATIC SPECIES/ The effects of two commonly used fertilizers, diammonium phosphate and urea, on hematological parameters (hemoglobin, red blood cell count, hematocrit, and total leucocyte count) of fresh water fish Clarias batrachus were studied. The toxic effect of diammonium phosphate was more pronounced than that of urea. The toxic effect of diammonium phosphate resulted in a sudden fall of hematological parameters--Hb, red blood cell count, Hct--at higher concentrations, and at lower concentrations gradual decreases were seen over comparatively longer durations. In urea intoxication, slight decreases in the three parameters were seen at lower concentrations during shorter intervals, while at higher concentrations, significant decreases during shorter intervals were observed. Total leucocyte count increased during toxicity with both fertilizers, but higher elevations in total leucocyte count were produced by diammonium phosphate than by urea.

According to the 2006 TSCA Inventory Update Reporting data, the number of persons reasonably likely to be exposed in the industrial manufacturing, processing, and use of diammonium phosphate is 1000 or greater; the data may be greatly underestimated(1).

Substances or mixtures that are added to the soil to supply nutrients or to make available nutrients already present in the soil, in order to increase plant growth and productivity. (See all compounds classified as Fertilizers.)|Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS. (See all compounds classified as Food Additives.)

Ingested diphosphate is readily converted to monophosphate; no diphosphate was found in feces or urine of rats treated with diets containing up to 5% tetrasodium diphosphate. In these experiments diphosphate was almost completely absorbed by the gut and excreted as monophosphate in the urine. /Diphosphate/|/Ortho/ phosphate is absorbed from, and to a limited extent secreted into, the gastrointestinal tract. Transport of phosphate from the gut lumen is an active, energy-dependent process that is modified by several factors. ... Vitamin D stimulates phosphate absorption, an effect reported to precede its action on calcium ion transport. In adults, about two thirds of the ingested phosphate is absorbed, and that which is absorbed is almost entirely excreted into the urine. In growing children, phosphate balance is positive. Concentrations of phosphate in plasma are higher in children than in adults. This "hyperphosphatemia" decreases the affinity of hemoglobin for oxygen and is hypothesized to explain the physiological "anemia" of childhood. /Phosphates/

In the animal body, diphosphate is formed from adenosyl triphosphate (ATP) in many enzymatic reactions. It is either utilized by entering phosphorolytic reactions, or it is hydrolysed by an inorganic diposphatase to monophosphate. /Diphosphate/|A defect in phosphate metabolism occurs in a variety of diseases. ... Rickets ... Osteomalacia ... Primary or Secondary Hyperparathyroidism ... Chronic Renal Failure. /Phosphates/

Wet process DAP: iron, aluminum and magnesium.

Fresh air, rest.

Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Ammonia and related compounds/|/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for signs of pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mg/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize. /Ammonia and related compounds/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ammonium and related compounds/|/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Phosphorus and related compounds/|For more Antidote and Emergency Treatment (Complete) data for DIAMMONIUM HYDROGEN PHOSPHATE (6 total), please visit the HSDB record page.

/SIGNS AND SYMPTOMS/ ... With large doses of ... ammonium /salts/, there arises the possibility of sufficient absorption to produce diuresis and systemic ammonia poisoning, particularly if material is administered parenterally. /Ammonium Salts/|/SIGNS AND SYMPTOMS/ Acute ... eye contact with concentrated alkali causes conjunctival edema and corneal destruction. Alkalies penetrate skin slowly. Extent of damage therefore depends on duration of contact. Chronic poisoning (from skin contact). Chronic dermatitis may follow repeated contact ... /Alkalies and Phosphates/|/OTHER TOXICITY INFORMATION/ This paper summarizes data on the factors involved in addiction and dependence to cigarettes. Nicotine has been intensively studied by the tobacco industry, for instance for its addictive effect at the lowest possible rates. The addition of diammonium phosphate and urea produces an alcalinization of the pH of cigarette smoke, and promotes the absorption and the trans-membrane passage of nicotine. The taste, the smell of smoke, and the visual aspect of the pack of cigarettes are also sensory components that promote addiction. Finally, menthol, sugar, cocoa and liquorice added to cigarettes also play a role in dependence and addiction to cigarettes by, for instance, making an anesthetic effect on the airways.

ammonium hydrogen phosphate

The substance can be absorbed into the body by inhalation of its aerosol.

Redness. Pain.

(INCL MONOAMMONIUM PHOSPHATE) 97% FOR FERTILIZERS; 1% FOR FIRE CONTROL; 1% FOR LIVESTOCK FEEDS; 1% IN MISCELLANEOUS APPLICATIONS (1972)|CHEMICAL PROFILE: Ammonium Phosphates. 100% fertilizers: diammonium phosphate 87% (49% domestic, 51% export); monoammonium phosphate 13% (60% domestic, 40% export). /Ammonium phosphates/|CHEMICAL PROFILE: Ammonium phosphates. 100% fertilizers: diammonium phosphate 85%; monoammonium phosphates 15%. Exports account for 50% of total ammonium phosphates production. /Ammonium phosphates/|Fertilizer, 98% (DAP, 70%; MAP 23%, other solid ammonium phosphates, 5%); industrial uses, 1.5%; animal feed, 0.5%. /Ammonium phosphates/|During the year ending June 30, 1990, DAP represented 38% of total U.S. fertilizer P2O5 usage.

Grades: technical; CP /chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity/; fertilizer; feed; dentifrice; highly purified, for phosphors; FCC /Food Chemicals Codex/.|The grade used medicinally is 98-99% pure.|Fertilizer grade, min 18% N, 46% P.

Agriculture, forestry, fishing and hunting|Phosphoric acid, ammonium salt (1:2): ACTIVE|Produced in large scale as fertilizer|The thermal route (for making phosphoric acid starting material) results in a food-grade acid of high purity and is too expensive for fertilizer production. Essentially all the acid used in fertilizer production is made by wet processes.

Agrochemicals -> Acaricides|Cosmetics -> Buffering|FIRE RETARDANTS

Food Additives -> ACIDITY_REGULATOR; FLOUR_TREATMENT_AGENT; RAISING_AGENT; YEAST_FOOD;