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Home > Encyclopedia > Tiamulin fumarate

Tiamulin fumarate

pharmaceutical raw materials
Tiamulin fumarate structure

Tiamulin fumarate 

structure
  • CAS No:

    55297-96-6

  • Formula:

    C28H47NO4S.C4H4O4

  • Chemical Name:

    Tiamulin fumarate

  • Synonyms:

    Acetic acid,2-[[2-(diethylamino)ethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester,(2E)-2-butenedioate (1:1);Acetic acid,[[2-(diethylamino)ethyl]thio]-,6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester,[3aS-(3aα,4β,5α,6α,8β,9α,9aβ,10S*)]-,(E)-2-butenedioate (1:1) (salt);Acetic acid,[[2-(diethylamino)ethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester,(2E)-2-butenedioate (1:1) (salt);3a,9-Propano-3aH-cyclopentacyclooctene,acetic acid deriv.;14-Deoxy-14-[(2-diethylaminoethyl)-mercaptoacetoxy]mutilin hydrogen fumarate;Sandoz 81723hfu;81723hfu;SQ 22947;Tiamutin;Tiamulin fumarate;Dynamutilin;Tiamulin hydrogen fumarate;Tiavet;Thiamutilin fumarate;Tiamupharm;Vievitin;56193-13-6;89708-74-7

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Tiamulin is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia.


Tiamulin fumarate is a carbotricyclic compound, a carboxylic ester and a cyclic ketone.

Tiamulin fumarate Basic Attributes

609.81

609.333557

259-581-6

29419090

Characteristics

167

4.67970

white powder

147-148°C

563℃

>110°(230°F)

soluble in water

2-8°C

Safety Information

UN28116.1/PG3

3

22

36

AG9560000

Xn

P301 + P312 + P330

H302

|Warning|H302 (89.29%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P304+P340, P305+P351+P338, P312, P330, P337+P313, P403+P233, P405, and P501|Aggregated GHS information provided by 57 companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

2-(diethylaminoethyl)thioacetoxymutilin

Tiamulin fumarate Use and Manufacturing

A derivative of Pleuromutilin. Antibacterial. Uses: For the treatment of swine pneumonia caused by Actinobacillus pleuropneumoniae and swine blood dysentery caused by Treponema swine dysentery. As a feed drug additive for pigs, it can promote weight gain. It is also effective for chicken chronic respiratory disease, mycoplasma pneumonia, and staphylococcal synovitis.

Computed Properties

Molecular Weight:609.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:12
Exact Mass:609.33353876
Monoisotopic Mass:609.33353876
Topological Polar Surface Area:167
Heavy Atom Count:42
Complexity:889
Defined Atom Stereocenter Count:7
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Price Analysis

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