Dichlorophenol Safety Data Sheets

no data available

If inhaled

Following skin contact

Following eye contact

Following ingestion

SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes and upper respiratory tract. Prolonged contact can cause damage to the eyes, severe irritation and burns. Exposure to this class of compounds may cause profuse sweating, intense thirst, abdominal pain, nausea, vomiting, diarrhea, cyanosis from methemoglobinemia, hyperactivity, stupor, blood pressure fall, hyperpnea, hemolysis, convulsions, collapse, coma and pulmonary edema followed by pneumonia. If death from respiratory failure is not immediate, jaundice and oliguria or anuria may occur. Other symptoms of exposure to this class of compounds may include headache, dizziness, rapid and difficult breathing, weakness, severe burns and internal damage. Chronic exposure may result in digestive disturbances, nervous disorders, skin eruptions and liver and kidney damage. Skin contact with this type of compound may result in softening and whitening of the skin, followed by the development of painful burns. Prolonged contact may lead to dermatitis. Local contact may also result in painless blanching or erythema and corrosion of the skin. Skin sensitivity reactions occur occasionally. ACUTE/CHRONIC HAZARDS: This compound may be harmful by inhalation, ingestion or skin absorption. It is an irritant of the skin, eyes, mucous membranes and upper respiratory tract; and prolonged contact may result in severe irritation or burns. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and hydrogen chloride gas. It is rapidly absorbed through the skin. (NTP, 1992)

Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

Wear self-contained breathing apparatus for firefighting if necessary.

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

Land Spill: Dig a pit, pond, lagoon, or holding area /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner/ to contain liquid or solid material. Cover solids with plastic sheet to prevent dissolving in rain or fire fighting water. Trichlorophenol

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

no data available

no data available

2,3-DICHLOROPHENOL is incompatible with acid chlorides, acid anhydrides and oxidizing agents. (NTP, 1992)

no data available

no data available

When heated to decomposition it emits toxic vapors of /hydrogen chloride/.

Acute toxicity

• Oral: LD50 Mouse (male CD-1 ICR) oral 2585 mg/kg.
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50; Species: Brachydanio rerio (Zebra fish); Concentration: 4.67 mg/L for 24 hr /Conditions of bioassay not specified in source examined
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age <72 hr); Conditions: freshwater, static; Concentration: 5190 ug/L for 24 hr (95% confidence interval: 4090-6300 ug/L); Effect: intoxication, immobilization />95% purity
• Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae); Conditions: freshwater, static; Concentration: 5000 ug/L for 96 hr; Effect: growth, general
• Toxicity to microorganisms: no data available

AEROBIC: 2,3-Dichlorophenol, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI I test(1). 2,3-Dichlorophenol, present at 60 ppm in Wiggins, Mississippi acidic sandy loam with a pH of 4.8, reached 90% transformation to unspecified intermediates in 55 days, with a half-life of 28 days(2); 2,3-dichlorophenol, present at 130 ppm in Austin, Texas basic sandy silt loam with a pH of 7.8, reached 90% transformation to unspecified intermediates in 25 days, with a half-life of 8 days(2). Approximately 100% of initially added 2,3-dichlorophenol had been degraded after 2-4 weeks of incubation in four freshwater pond sediments(3); the chlorine at the 2-position was the most susceptible to the reductive dechlorination which occurred(3). After a lag period of approximately 2 weeks, 100% of the 2,3-dichlorophenol initially added to a freshwater pond sediment (which had been contaminated with asphalt) was observed to degrade within two weeks(3).

A BCF of 7.5 to 35 was measured in fish for 2,3-dichlorophenol using carp (Cyprinus carpio) which were exposed over a six week period to a water concentration of 30 ppb, according to the standard test of the Japanese Ministry of Industry and Trade (MITI)(1). According to a classification scheme(2), this BCF suggest the potential for bioconcentration in aquatic organisms is low(SRC).

An average Koc of 426 has been measured in three types of lake and river sediments(1). According to a classification scheme(2), this Koc value suggests that 2,3-dichlorophenol is expected to have moderate mobility in soil. The pKa of 2,3-dichlorophenol is 7.7(3), indicating that this compound will partially exist in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/