Metribuzin Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | Metribuzin |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | 4-amino-6-tert-butyl-4,5-dihydro-3-methylthio-1,2,4-triazin-5-one; 4-amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one; Lexone DF |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Herbicide |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Warning |
| Hazard statement(s) | H302 Harmful if swallowed H410 Very toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. |
| Response | P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P391 Collect spillage. |
| Storage | none |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| Metribuzin | Metribuzin | 21087-64-9 | 244-209-7 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest.
Following skin contact
Rinse and then wash skin with water and soap.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Rest.
4.2 Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Target Organs: central nervous system, thyroid, liver (NIOSH, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Skin decontamination: Skin contamination should he treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be, obtained without delay.
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Use water spray, powder.
5.2 Specific hazards arising from the chemical
Combustible.
5.3 Special protective actions for fire-fighters
Use water spray, powder.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Store in an area without drain or sewer access.Estimated shelf life in excess of 2 yr under normal storage conditions.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
TLV: 5 mg/m3, as TWA; A4 (not classifiable as a human carcinogen)
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety spectacles.
Skin protection
Protective gloves.
Respiratory protection
Use ventilation (not if powder), local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | Metribuzin is a colorless crystalline solid. Used as an herbicide. (NIOSH, 2016) |
|---|---|
| Colour | Colorless crytals |
| Odour | Weak characteristic odor |
| Melting point/freezing point | 125ºC |
| Boiling point or initial boiling point and boiling range | 312.4ºC at 760 mmHg |
| Flammability | Noncombustible Solid |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | 142.7ºC |
| Auto-ignition temperature | no data available |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | 0.1 % (NIOSH, 2016) |
| Partition coefficient n-octanol/water | log Kow= 1.7 |
| Vapour pressure | 0.000531mmHg at 25°C |
| Density and/or relative density | 1.28 |
| Relative vapour density | no data available |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Decomposes on burning. This produces toxic fumes including nitrogen oxides and sulfur oxides.
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
NonflammableA triazine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
This compound is incompatible with the following:None reported (NIOSH, 1997)
10.6 Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /nitrogen oxides and sulfur oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 1100 mg/kg
- Inhalation: no data available
- Dermal: LD50 Rat percutaneous >20,000 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Reproductive toxicity
no data available
STOT-single exposure
Exposure at high levels could cause depression of the central nervous system.
STOT-repeated exposure
no data available
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 Rainbow trout 64 mg/l/96 hr and bluegill sunfish 80 mg/l/96 hr
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
In mineral and muck soils, metribuzin metabolism via deamination and thiodealkylation produced: 6-(1,1-dimethylethyl)-3-methylthio-1,2,4-triazin-5- (4H)-one metribuzin; 4-amino-6-(1,1-dimethylethyl)-1,2,4-triazin-3,5-(2H,4H)- dione 3,5-diketo; and 6-(1,1-dimethylethyl)-1,2,4-triazin-3,5-(2H,4H)-dione deaminated diketo. Over a pH range of 4.5 to 6.9 in sandy clay loam, microbial degradation gave (14)CO2 from (14)C ring-labeled metribuzin. It was also observed that metribuzin degradation by soil microoganisms decreased with increasing soil pH.
12.3 Bioaccumulative potential
The bioconcentration factor (BCF) of metribuzin in the Golden ide fish (Leuciscus idus melanotus) was experimentally determined to be 10 in a 3 day static test(1). According to a classification scheme(2) and this BCF value, metribuzin is not expected to bioconcentrate in aquatic organisms(SRC).
12.4 Mobility in soil
The average Koc of metribuzin is 60(1). Parent metribuzin was very mobile in sandy (0.58% OC), sandy loam (0.64% OC), silt loam (1.7% OC), and clay loam (1.3% OC) soils with adsorption(1). Freundlich constant values of 0.25, 0.02, 0.22, and 0.20, respectively desorption Freundlich values were 0.56, 0.14, 0.51, and 0.41, respectively(1). Adsorption Koc were 47, 3, 15, and 17 and desorption Koc values were 106, 24, 33, and 36, respectively(1). The Koc values for metribuzin in Alaskan subarctic agricultural silt loam soils ranges from 34-56(2). Experimental Koc values have been measured for sand (Koc=47; 1% OM, pH 4.3), sandy loam (Koc=3; 1.1% OM, pH 6.6), silt loam (Koc=14; 3% OM, pH 5.9), and clay loam (Koc=17; 2.2% OM, pH 6.4) soils(1). Metribuzin has high affinity for soil organic matter, but is less tightly adsorbed to clay(1). Adsorption of metribuzin decreases as soil pH increases(1). According to a classification scheme(4), these Koc values suggest that metribuzin is expected to have high mobility in soil(SRC).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN3077 (For reference only, please check.) | IMDG: UN3077 (For reference only, please check.) | IATA: UN3077 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.) | IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.) | IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 9 (For reference only, please check.) | IMDG: 9 (For reference only, please check.) | IATA: 9 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: III (For reference only, please check.) | IMDG: III (For reference only, please check.) | IATA: III (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: Yes | IMDG: Yes | IATA: Yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| Metribuzin | Metribuzin | 21087-64-9 | 244-209-7 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Not Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Not Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
Metribuzin is included in Herbicides category.
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