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Khurram Shezad

Anthrone reagent protocol

Bergen Furniture And Design  Follow

Anthrone method is not a method for estimating tissue glycogen. It is used for measuring  carbohydrates- either free or present in polysaccharides.

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Bernard Thompson  Follow


Anthrone reagent: 0.2 % anthrone in conc. H2SO4
Take 1ml of sample/standard in the test tube. (Use 1ml distilled water in a separate tube as a blank/negative control)
Add 3ml of anthrone reagent to all the tubes. Mix thoroughly by vortexing.
Close/seal the cap of all tubes, incubate at 90 C for 15 -20 minutes. It will produce greenish colour.
Cool down all the samples/tubes at room temperature
Take OD at 625 using a spectrophotometer.

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Armand Wong Sr.  Follow
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Anita Handa-Corrigan  Follow

We dissolved Anthrone in 98% concentrated sulfuric acid. For the preparation of the standard curve, sucrose solutions were prepared, we need this carbon source.
2: 1 volume of anthrone reagent was added to each solution and it was kept in a water bath at 100 degrees C for 10 minutes. but we got a dark solution, and not the recurring colors, even changing 3: 1 volume of anthrone and solution
do you have a comment for us ????

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David Colasante  Follow

@zahir hussain- sir can u please suggest me some protocol for total glycogen estimation?

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Ciel Phantomhive  Follow

The anthrone method per se will measure all carbohydrates in a sample, including glycogen, glucose, glycolipids, glycoproteins, etc.

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Donald Hubbs  Follow

Those polymers which are made up of glucose unit can be measured using Anthrone reagent. Find the attached file having protocols for estimation of glycogen from animal muscle and organs

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