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+ Medical research
+ Biochemistry
+ Chemistry
+ Bone research
+ Tissue engineering
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Neela Fazl

Can anyone help me with fast green/safranin O staining of...

Chris Phillips  Follow

Down-loaded from musculoskeletal research center, University of Rochester- the enclosed protocol has worked very well for me on micromass chondrogenesis paraffin sections and knee articular cartilage of rat. I do not see why it should not work in your case. Very well written by Matt Hilton. Pl find as an attachment

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Armand Welsh  Follow

PFA the video its very well explained.

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Adam Jacholkowski  Follow

Only my worry is you are trying to chondrogenesis in monolayer. Try also micromass to compare.

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Brian Dave  Follow




Hi! Yesterday, I stained the above protocol on my 2D sample.
It worked seamlessly. The tip is I permeabilized the culture with 0.1% Triton X 100 in PBS for 20 min before washing and acetic incubation step.

1. Fixe sample as usual.
2. Permeabilize cells with 0.1% Triton X 100/20 min RT
3. Wash x3 with PBS
4. 1% acetic acid 10 seconds
5. 1% Safranin O 5 min
6. wash x2 with PBS
7. observe


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Carol Dixon  Follow
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