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Confused about identifying delocalized electron pairs in Isoniazid
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Matt Robinson
Confused about identifying delocalized electron pairs in Isoniazid
The reason why the amine lone pair is delocalized is that to make the last conformer you proposed, the nitrogen closest to the oxygen would have to form five bonds. Nitrogen is a second-row element that cannot readily possess 10 electrons from those 5 bonds, even if nitrogen has to possess those 10 electrons for the very short time required for the electrons to switch conformations between different resonance conformers.
The reason why the amine lone pair is delocalized is that to make the last conformer you proposed, the nitrogen closest to the oxygen would have to form five bonds. Nitrogen is a second-row element that cannot readily possess 10 electrons from those 5 bonds, even if nitrogen has to possess those 10 electrons for the very short time required for the electrons to switch conformations between different resonance conformers.
The reason why the amine lone pair is delocalized is that to make the last conformer you proposed, the nitrogen closest to the oxygen would have to form five bonds. Nitrogen is a second-row element that cannot readily possess 10 electrons from those 5 bonds, even if nitrogen has to possess those 10 electrons for the very short time required for the electrons to switch conformations between different resonance conformers.
The reason why the amine lone pair is delocalized is that to make the last conformer you proposed, the nitrogen closest to the oxygen would have to form five bonds. Nitrogen is a second-row element that cannot readily possess 10 electrons from those 5 bonds, even if nitrogen has to possess those 10 electrons for the very short time required for the electrons to switch conformations between different resonance conformers.
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