As you mentioned, under the Friedel Craft Reaction condition, the aniline (a Lewis base) binds to the electrophile AlCl3 (a Lewis acid) to give a coordination complex (a salt). Then, the positive charge on the nitrogen is electron withdrawing, and it pulls the electron density of the aromatic ring by negative inductive effect (-I effect). It therefore, deactivates the ring for further acylation reactions. Finally, the complex precipitates out of the reaction mixture and the acylation reaction is not observed.
As you mentioned, under the Friedel Craft Reaction condition, the aniline (a Lewis base) binds to the electrophile AlCl3 (a Lewis acid) to give a coordination complex (a salt). Then, the positive charge on the nitrogen is electron withdrawing, and it pulls the electron density of the aromatic ring by negative inductive effect (-I effect). It therefore, deactivates the ring for further acylation reactions. Finally, the complex precipitates out of the reaction mixture and the acylation reaction is not observed.
Dear Noor jaisha Aslam,
As you mentioned, under the Friedel Craft Reaction condition, the aniline (a Lewis base) binds to the electrophile AlCl3 (a Lewis acid) to give a coordination complex (a salt). Then, the positive charge on the nitrogen is electron withdrawing, and it pulls the electron density of the aromatic ring by negative inductive effect (-I effect). It therefore, deactivates the ring for further acylation reactions. Finally, the complex precipitates out of the reaction mixture and the acylation reaction is not observed.
Kind regards.
Dear Noor jaisha Aslam,
As you mentioned, under the Friedel Craft Reaction condition, the aniline (a Lewis base) binds to the electrophile AlCl3 (a Lewis acid) to give a coordination complex (a salt). Then, the positive charge on the nitrogen is electron withdrawing, and it pulls the electron density of the aromatic ring by negative inductive effect (-I effect). It therefore, deactivates the ring for further acylation reactions. Finally, the complex precipitates out of the reaction mixture and the acylation reaction is not observed.
Kind regards.
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thanks Exequiel Porta
thanks Exequiel Porta
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