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Kevin Landgrebe

Glucose concentration and HEPES in Jurkat cell culture?

Alvin Funk  Follow

Hey, I was wondering the same, did you manage to find an answer to the glucose question?

The Hepes seems to be a more stable buffer. A microscopy person told me, they use it as a buffer for their live cell microscopy for up to 48h outside of the incubator.

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Debra Barnett  Follow

I ended up adding glucose to the culture in the beginning to reach the 4500 mg/L, but once the cells started growing I saw no big differences in proliferation between the higher and lower (2000 mg/L) cultures. However, probably probably the glucose level will have an effect on the cells functionality in some ways, but I found to clear answer to what amount of glucose would be best (also some conflicting information). If you find a better answer to this, please let me know too!

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