Help on the solubility of curcumin in different solvents

If you scroll down on this page you have some data, curcumin is not very soluble:
https://www.scbt.com/p/curcumin-458-37-7

Its probably a lot different in alkaline water, it should be very soluble in 0.1M NaOH.

@OP,
Why would solubility of curcumin be dependent upon pH?  Also, there is acetone to consider as a possible solvent.  What are its properties?

Solubility doesn't work like that. It might very well be soluble in solvents that fall in between water and hexane (in terms of polarity).

I just asked a friend who did their PhD in curcumin. Said acetone is best, about 50mg/ml, then ethanol and method about 10mg/ml depending on the purity of curcumin.

Like you , I cannot find exact solubilities in different solvents.

However, curcumin is listed as soluble in methanol, ethanol, glacial acetic acid.

Looking at the structure of curcumin, I wonder if toluene, one of the xylenes, or ethylbenzene may be suitable.

The solvent to use depends somewhat on the proposed use of the solution.

Some higher boiling solvents, NOT really suitable for chromatography, to try would be

DMSO (dimethyl sulfoxide)
N,N-DMF (N, N-dimethylformamide)
HMPA (hexa-methyl-phosporic triamide)
Pyridine.

Maybe even glycerol or hydroxymethyl-benzene.

Solubility in DMSO is in my last post if you scroll down. HMPA is carcinogenic so its in most labbs forbidden to use, at least here in Sweden.