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How can we protect NH2 functional groups and deprotect?
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+ Chemical organic synthesis
+ Chemical crosslinking
+ Carbohydrate biochemistry
+ Organic synthesis
+ Organic polymer
Posted by
Mark Cox
How can we protect NH2 functional groups and deprotect?
I want to use EDC/NHS to attach COOH on NH2 group of my polymer.The polymer has three arms, all of them have NH2 groups.However, I want one arm to attach to COOH group of molecular A, another two arms to attach to COOH group of molecular B.Is there any protecting group I can use to protect the two arms first, and then, after polymer react to COOH of molecular A, deprotect, and add B later?PS. A is another long length polymer, and B is Heparin (structure is on Link).http://en.wikipedia.org/wiki/Heparin#mediaviewer/File:Heparin-2D-skeletal.png
