Home >
Community >
How to determine pore size of a hydrogel upfront?
Upvote
26
Downvote
+ Microfluidics
+ Polymerization
+ Hydrogel
+ Chemistry
Posted by
Atthahirah Hadijah
How to determine pore size of a hydrogel upfront?
Currently I am working on a microfluidic chip. An integral part of it should be a semi-permeable membrane which allows the flow of H2O and smaller ions (nothing bigger than a dinucleotide) but effectively blocks all DNA bigger than 12 nt.For in situ polymerisation I use PEGDA (~MW = 700, others are in the shelf), a photostarter (Darocur 1153) and some water. Polymerisation starts with UV exposure and so far everything goes fine, the structure is where I need it to be and the mechanical stability also according to the requirement.Is there a way to calculate the pore size upfront or a table where I can look up which composition leads to which result?
