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Juana Mangaoang

How to dissolve L-cystine for biological assays?

Chandrakala Chaulagain  Follow

Hello Tik Hang Soong

Alternatively, you can use N,N'-di-L-alanyl-L-cystine which is a product made by coupling two molecules of L-alanine to a molecule of L-cystine. This product, Cys-dipeptide is 20 times more soluble than L-cystine.

L-cystine solubility is 1mM at pH 7 while Cys-dipeptide solubility is > 30mM at pH 7.

Please refer to the links below for more information on this product.

https://patents.google.com/patent/EP0264953A2/en

https://www.chemsrc.com/en/cas/115888-13-6_508430.html#nameDiv

Best.



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