HRMS is a high resolution mass spectrum which has a more accurate molecular mass it means it can distinguish the difference between the interference ions which has a very similar parent ion with the target ion and the target ions. Besides, HRMS should be more sensitive than the LC-MS according to my experience. As the HRMS has a different working ways with LC-MS. The working you need to do is to search the data base to get the accurate molecular weight and adducts ions, and tune you target compounds to get verification. I would not recommend you follow the LC/MS protocol but for the LC condition. Good luck.
HRMS is a high resolution mass spectrum which has a more accurate molecular mass it means it can distinguish the difference between the interference ions which has a very similar parent ion with the target ion and the target ions. Besides, HRMS should be more sensitive than the LC-MS according to my experience. As the HRMS has a different working ways with LC-MS. The working you need to do is to search the data base to get the accurate molecular weight and adducts ions, and tune you target compounds to get verification. I would not recommend you follow the LC/MS protocol but for the LC condition. Good luck.
Thank you Dr. Weichao...
Thank you Dr. Weichao...
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Dear ,
you should go with HRMS ,
best for good quality publication.
Manoj
Dear ,
you should go with HRMS ,
best for good quality publication.
Manoj
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HRMS is a high resolution mass spectrum which has a more accurate molecular mass it means it can distinguish the difference between the interference ions which has a very similar parent ion with the target ion and the target ions.
Besides, HRMS should be more sensitive than the LC-MS according to my experience. As the HRMS has a different working ways with LC-MS. The working you need to do is to search the data base to get the accurate molecular weight and adducts ions, and tune you target compounds to get verification. I would not recommend you follow the LC/MS protocol but for the LC condition.
Good luck.
HRMS is a high resolution mass spectrum which has a more accurate molecular mass it means it can distinguish the difference between the interference ions which has a very similar parent ion with the target ion and the target ions.
Besides, HRMS should be more sensitive than the LC-MS according to my experience. As the HRMS has a different working ways with LC-MS. The working you need to do is to search the data base to get the accurate molecular weight and adducts ions, and tune you target compounds to get verification. I would not recommend you follow the LC/MS protocol but for the LC condition.
Good luck.
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What is the difference between hrms LCMS peak
What is the difference between hrms LCMS peak
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Surendhra Nadh Go for HR LCMS
Then you will get best results.
Surendhra Nadh Go for HR LCMS
Then you will get best results.
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