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Is scopolamine same as scopolamine hydrobromide?
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KC.Campbell122
Is scopolamine same as scopolamine hydrobromide?
If the extraction procedure does not involve HBr, then I would doubt it is the hydrobromide because:
hydrobromide salts don't dissolve well in acetone;
hydrobromide salts are rare in nature.
According to the work by Bracci et al. [1], the major component of MeOH extraction of Brugmansia is atropine.
Śramska et al. [2] used ethyl acetate extraction and isolated scopolamine and atropine.
No mention of hydrobromide salts in either.
References
Bracci, A.; Daza-Losada, M.; Aguilar, M.; De Feo, V.; Miñarro, J.; Rodríguez-Arias, M. A Methanol Extract of Brugmansia Arborea Affects the Reinforcing and Motor Effects of Morphine and Cocaine in Mice. Evidence-Based Complementary and Alternative Medicine2013, 2013, 1–7. https://doi.org/10/f96zpc.
Śramska, P.; Maciejka, A.; Topolewska, A.; Stepnowski, P.; Haliński, Ł. P. Isolation of Atropine and Scopolamine from Plant Material Using Liquid-Liquid Extraction and EXtrelut® Columns. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.2017, 1043, 202–208. https://doi.org/10/f9wvv8.
If the extraction procedure does not involve HBr, then I would doubt it is the hydrobromide because:
hydrobromide salts don't dissolve well in acetone;
hydrobromide salts are rare in nature.
According to the work by Bracci et al. [1], the major component of MeOH extraction of Brugmansia is atropine.
Śramska et al. [2] used ethyl acetate extraction and isolated scopolamine and atropine.
No mention of hydrobromide salts in either.
References
Bracci, A.; Daza-Losada, M.; Aguilar, M.; De Feo, V.; Miñarro, J.; Rodríguez-Arias, M. A Methanol Extract of Brugmansia Arborea Affects the Reinforcing and Motor Effects of Morphine and Cocaine in Mice. Evidence-Based Complementary and Alternative Medicine2013, 2013, 1–7. https://doi.org/10/f96zpc.
Śramska, P.; Maciejka, A.; Topolewska, A.; Stepnowski, P.; Haliński, Ł. P. Isolation of Atropine and Scopolamine from Plant Material Using Liquid-Liquid Extraction and EXtrelut® Columns. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.2017, 1043, 202–208. https://doi.org/10/f9wvv8.
Any information on whether extracted scolopamine is the devils breath? By the what I think extraction is acetone. PubChem says hyoscine is soluable in acetone and doesnt mention acetone in atropine or hyoscyamineMore
Hyoscine is the commercial name for the medical product containing scopolamine that is used to treat motion sickness etc. It is sometimes formulated as the hydrobromide to make it more water soluble and easier to take.More
If the extraction procedure does not involve HBr, then I would doubt it is the hydrobromide because:
According to the work by Bracci et al. [1], the major component of MeOH extraction of Brugmansia is atropine.
Śramska et al. [2] used ethyl acetate extraction and isolated scopolamine and atropine.
No mention of hydrobromide salts in either.
References
If the extraction procedure does not involve HBr, then I would doubt it is the hydrobromide because:
According to the work by Bracci et al. [1], the major component of MeOH extraction of Brugmansia is atropine.
Śramska et al. [2] used ethyl acetate extraction and isolated scopolamine and atropine.
No mention of hydrobromide salts in either.
References
More
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