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Mark Wedrall

MALDI matrix problem

Chris Calone  Follow
I do MALDI Imaging.DHB and CHCA are my main Matrix.DHB is poor crystals, which is recognized.Crystal Size is very large.I now use Sublimation to complete DHB crystals. The crystallization effect of DHB is particularly good. Crystal Size is below 5 microns.

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David Plantz  Follow
Use ethanol or acetone as a solvent to configure the DHB matrix solution. After the crystallization, there will be no strong large crystal blocks, and it is easy to be stimulated by laser signals.If you must use a DHB aqueous solution, first click a sample to crystallize, and then dissolve the crystallized point with pure water solvents and then the crystallization of the crystallization can also weaken the effect of DHB to form a firm large crystal block.

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