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Mohamad Bawa

Pseudo chiral centre

Anders Wahlberg  Follow

Consider this molecule

Carbon number 4 is a pseudo chiral center because its chirality depends on the chirality of the second and sixth carbons. For example, if the second carbon is S and the sixth carbon is R, then carbon number 4 can be r or s, but if the chirality of the second and sixth carbons are the same, then carbon number 4 is not the chiral center, because it doesn't have 4 different groups around itself.

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Isaac To  Follow
ursula.chem.yale.edu/~chem220/chem220js/STUDYAIDS/isomers/…More
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James Leach Jr  Follow
When C2/C6 are of different configurations (R/S), C4 will be stereogenic and achirotopic (r/s). When C2/C6 are of the same configurations (R/R or S/S), C4 will be chirotopic and non-stereogenic. There is no r/s assignment. See: More
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David Thomas  Follow

Pseudoassymetric center is the carbon that show chirality and achirality simultaneously.The r/s (not R/S) nomenclature of carbon 4 depend on R/S configuration of directly attached carbon atom.In the given molecule the carbon 4 is attached with constituitionaly same but configurationaly different group so it is a chiral center (note: R configuration has priority over S configuration). if we imagine it has a plane of symmetry and that make it achiral.

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Doug Franzen  Follow
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Iain MacLeod  Follow
of chirality; the two are mutually exclusive. Like e.g., is an information More
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Eta Vugakoto  Follow
chiral and achiral when the leading «a» in «achiral» denotes the More
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John  Follow
absenceMore
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Faiz Marsad  Follow
publicMore
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