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Mehak Jones

What drugs interact with nitrous oxide?

Andi Quercia  Follow

MDMA. I have a vast amount of experience with high dose nitrous oxide, which can be intense to the point of matching DMT or LSD (albeit very short lived).

Low dose nitrous tends to be pretty sedate, “laughing gas” isn't a bad description for the odd puff in a balloon. However… 100mg of MDMA certainly changed things. One balloon took me from standard MDMA high to a full blown psychedelic trip similar 300ug of LSD. It faded quickly, but was pretty unexpected and intense, especially being seated on the floor during a warehouse party. Definite solid interaction with MDMA there, even at a very low nitrous dose.

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