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Kara Krelove

What is the reaction amide with NaOH?

Michael  Follow

First you look there this is the reaction name acid - base reaction in this first -OH group attack on carbon atom and the bond between c and oxygen turn upper side and oxygen will be negatively charge and with this sodium is come in contact with negatively charged oxygen and with this amide group attach with R-c=o is leave the group and take electron with itself and carbon will positively charge and with that oxygen try to give electron to carbon and with this hydrogen will leave the oxygen atom and connect with amide group . This process is called deprotonation .

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Bob  Follow

I take it, you are talking about the basic hydrolysis of amides. Upon reacting an amide with aqueous sodium hydroxide, you hydrolise the amide bond to form an amine and an aqueous solution of a sodium salt.

If the amide is, say, ethaneamide, by heating it with aqueous sodium hydroxide ammonia is given off (it can be distilled off) and you're left with aqueous sodium acetate (ethanoate).

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