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Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?
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Loren McCune
Why Nucleophilic substitution of pyridine undergoes at C2 and C4 but not on C3?
Draw the mechanism, including all resonance structures for the anionic intermediate. Then, think about them. Where is negative charge more stable in anions? That will explain it.
Draw the mechanism, including all resonance structures for the anionic intermediate. Then, think about them. Where is negative charge more stable in anions? That will explain it.
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