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Misha Firer

Bromination of a propargyl alcohol

Arslan Siddique  Follow
PBr3 SURELY!  As stated, you will get the allene with Finkelstein if the temp is not uber cold!  Too expensive to conduct, and 2 steps as you said.
      -Zack

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Brian White  Follow
Finkelstein needs low temp to avoid allene formation.
PBr3 is probably the way to go.

Have not done either for a long time now :(

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Colin Watters  Follow
I am not doing finkelstein.

I found a great procedure in a book by a chemist named Brandsma.  Has exactly what I need.

Done in ether with a bit of pyridine at -35.  Then bring to rt and reflux for 30 min.

Not bad.

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Dave Jain  Follow
ORgopete,

I understand.  We are trying to make starting materials so it is cheaper.  On scale, it will be cheaper.

The PBr3 is the route to take here. 

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Courtney Villeda  Follow
I cannot tell you whether this is good advice or not, but I'd look up your target compound. It looks simple enough that I assume it is known. (For kicks, I'd sometimes compare what they were paying me with the cost of trying a "new" route to a known compound. I didn't try too many new routes. It just wasn't worth it. That is also why I bought something if I could. Just sayin.)

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