Cyanoic acid hydrolysis

Cyanoli wants to use acidic hydrolysis, improve three methods to give you reference: 1, concentrated hydrochloric acid heating back water solution, the characteristics of the reaction rate is slow, may be longer in the middle state residence time of the amide; 2, concentrated sulfuric acid to 120-150 degree (specifically you can try it yourself) hydrolysis, the characteristics reaction speed is very fast, the amide intermediate state residence time will be shorter; 3, 70-80% sulfuric acid solution heating back water, the characteristics of the reaction is also faster, moreSuitable for some cyanohydroxidation of a larger resistance!

The next pair, but as experiments, please note that acid hydrolysis often has highly toxic gases,

The methanol of hydrochloride changes directly to methyl esters, and the hydrochloric acid is often higher than the yield.