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Mark Goodwillie

DMF removal from water soluble product

Art Cronk  Follow
Toluene azeotropes are often used in industry to remove things like this. It is really easy to do in a plant.

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Brad Walter  Follow
I always use acetone for hydrochlorides. However I have never used this particular salt.

Also when something is in DMF it never seems to want to come out.

I take it your plant cannot get enough heat and vacuum to just distill it off? then azeotrope a couple of times with toluene?

This is how I do it in the lab but this is impractical on a commercial scale

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