Home > Community > How to predict protein secretion systems in bacterial genomes?
Upvote

19

Downvote
+ Bioinformatics analysis
+ Genome
+ Secretion
Posted by
Matt

How to predict protein secretion systems in bacterial genomes?

Affan Khadir  Follow

excellent list, I was while ago helping updating following resource:
https://effectors.csb.univie.ac.at/


More

Upvote

VOTE

Downvote
Nigel West  Follow


McDermott et al 2010, Computational Prediction of Type III and IV Secreted Effectors in Gram-Negative Bacteria, Infection and Immunity Dec 2010, 79 (1) 23-32; DOI: 10.1128/IAI.00537-10

Xiong et al 2018, PredT4SE-Stack: Prediction of Bacterial Type IV Secreted Effectors From Protein Sequences Using a Stacked Ensemble Method, Frontiers in Microbiology, DOI=10.3389/fmicb.2018.02571

Eichinger et al 2016, EffectiveDB--updates and novel features for a better annotation of bacterial secreted proteins and Type III, IV, VI secretion systems.Nucleic Acids Res. 2016 Jan 4;44(D1):D669-74. doi: 10.1093/nar/gkv1269. Epub 2015 Nov 20.

More

Upvote

VOTE

Downvote
Anil Mukhiya  Follow

You can send the protein fasta file from your annotated genome to KofamKOALA. It uses HMM to annotate the metabolic pathways of your bacteria. There is a section in results to list all secretion systems found.

https://www.genome.jp/tools/kofamkoala/

More

Upvote

VOTE

Downvote