How to remove dimethyl sulfoxide, product is dissolved in water

There is also a method directly plus the polar solvent into, such as diethyl ether, petroleum ether, n-hexane, to see if you can give your product

If you get the product is not boiling with water, you can try to add water to the water and then steam, steam, use a pump that is large with an exhaust, don't look at the true space, use water to bring DMSO out

EtOAc EtOAc EtOAc EtOAc

Decompression, your vacuum pump is not working, with high power oil pumps or diaphragm pumps.

The product is soluble in water and DMSO, indicating that the polarity is large, and it can be attempted to add a low polar solvent to precipitate the product

EtOAc EtOAc EtOAc EtOAc

Paste the structure, everyone may give you a better suggestion.

Decompression, your vacuum pump is not working, with high power oil pumps or diaphragm pumps.

Different at low temperature DMSO and water ice point

In addition to DMSO, it is preferred to use diethyl ether, and DMSO is small in diethyl ether, then washed with water, the product is dissolved in water, and the aqueous phase is extracted several times with diethyl ether, which should be lost.It is then concentrated on a rotary evaporator (it is steaming, which is reduced pressure distillation).DMSO was not clean with ethyl acetate or dichloromethane.
DMSO boiling point 189, decompression distillation can also (using oil pump, temperature heating to 100 degrees, there is no problem, no good high), your product boiling point must be relatively high.It is recommended to use extraction.
If there is not much, your product and DMSO's RF value are obvious, and column chromatography can also be purified.(Many times a few times, in the first time, in the first time, it will be good behind it)
I hope to help!

Steam

Paste the structure, everyone may give you a better suggestion.

Different at low temperature DMSO and water ice point

There is also a method directly plus the polar solvent into, such as diethyl ether, petroleum ether, n-hexane, to see if you can give your product

The product is soluble in water and DMSO, indicating that the polarity is large, and it can be attempted to add a low polar solvent to precipitate the product

Fluorescent dyes are generally purified by the preparative method, and can be purified or removed with C18 columns

Fluorescent dyes are generally purified by the preparative method, and can be purified or removed with C18 columns

Steam

In addition to DMSO, it is preferred to use diethyl ether, and DMSO is small in diethyl ether, then washed with water, the product is dissolved in water, and the aqueous phase is extracted several times with diethyl ether, which should be lost.It is then concentrated on a rotary evaporator (it is steaming, which is reduced pressure distillation).DMSO was not clean with ethyl acetate or dichloromethane.
DMSO boiling point 189, decompression distillation can also (using oil pump, temperature heating to 100 degrees, there is no problem, no good high), your product boiling point must be relatively high.It is recommended to use extraction.
If there is not much, your product and DMSO's RF value are obvious, and column chromatography can also be purified.(Many times a few times, in the first time, in the first time, it will be good behind it)
I hope to help!

If you get the product is not boiling with water, you can try to add water to the water and then steam, steam, use a pump that is large with an exhaust, don't look at the true space, use water to bring DMSO out