methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
The moderator has spoke, says, in fact, this is the reaction I am not good at, but also to do this kind of reaction
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123] Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
The moderator has spoke, says, in fact, this is the reaction I am not good at, but also to do this kind of reaction
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123] Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
The moderator has spoke, says, in fact, this is the reaction I am not good at, but also to do this kind of reaction
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123] Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
The moderator has spoke, says, in fact, this is the reaction I am not good at, but also to do this kind of reaction
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123] Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
More
VOTE
More
VOTE
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
More
VOTE
More
VOTE
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123]
Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123]
Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
More
VOTE
More
VOTE
More
VOTE
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123]
Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
, the mechanism is, but not well, the landlord can Take a look at the cultural media of the Technological Materials of Dalian University. There is Yao Mengzheng Yang Jinzhong (already) Wu Zuwang Cheng Lu Bo's compilation, order name may be incorrect
with amino group, usually after mixing of dimethyl, Slowly add the alkali at a certain temperature, in fact, even if the base is not added, the reaction has begun, because the amino group is a base, the secondary amine amine is also, the alkali is to make the reaction to the bottom, the product is a tertiary amine [ 123]
Exactly, it is exactly that it is necessary to have a phenolic hydroxyl group and an alcohol hydroxyl group, and a polymethyl group is desirably
phenolic hydroxyl group is generally phenol sodium phenol, then sodium hydroxide, then Dimethyl dimethyl or phenol ester can also be mixed with a liquid base (as high as possible)
With regard to ratio, dimethyl sulfate can only be used with a methyl, so the ratio is not wrong. Generally, it is generally more than 10% to 50% or even higher. It is generally said that the raw material disappears is the end point
, this is a competitive reaction
Generally, amino and phenol The hydroxy compound is easily methylated, and the acidic acid is more sodium hydroxide, and there is sodium hydroxide, sodium carbonate, sodium bicarbonate, triethylamine, dimethylaminopyridine, etc., this is specific to the specific problem
The landlord can have any questions in the experiment process
More
VOTE
More
VOTE
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
methylation, regardless of N or O methization, its reaction rate is faster than hydrolysis (alkali) (dimethyl sulphate oil solubility, andThe organism is more likely to be combined), in this system, methylation is the main reaction, hydrolysis is secondary, does not occupy the dominant
, and there is a similar, such as an anhydride amidation, although in the water medium, butThe amidation is the main body, the anhydride hydrolysis is the secondary
sulfate quench, mainly to form ester sodium salt without volatile
More
VOTE