Recuperation of the free base: Neutralization → solvent evaporation → extraction in dichlomethane → removing of the aqueous phase → drying with Na2SO4 → dichloromethane evaporation. Salt formation: Solution in an oxygen containing solvent (e.g. THF, ethanol , isopropanol, etc.) → saturation with gaseous HCl at oC, (ice bath ) up to acidic to litmus (open flask in the fume cupboard) → cupping and storing in the refrigerator, overnight → filtration. If not equipped, try an organic acid. But, where is the sodium comes from?
Recuperation of the free base: Neutralization → solvent evaporation → extraction in dichlomethane → removing of the aqueous phase → drying with Na2SO4 → dichloromethane evaporation. Salt formation: Solution in an oxygen containing solvent (e.g. THF, ethanol , isopropanol, etc.) → saturation with gaseous HCl at oC, (ice bath ) up to acidic to litmus (open flask in the fume cupboard) → cupping and storing in the refrigerator, overnight → filtration. If not equipped, try an organic acid. But, where is the sodium comes from?
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Neutralization → solvent evaporation → extraction in dichlomethane → removing of the aqueous phase → drying with Na2SO4 → dichloromethane evaporation.
Salt formation:
Solution in an oxygen containing solvent (e.g. THF, ethanol , isopropanol, etc.) → saturation with gaseous HCl at oC, (ice bath ) up to acidic to litmus (open flask in the fume cupboard) → cupping and storing in the refrigerator, overnight → filtration.
If not equipped, try an organic acid.
But, where is the sodium comes from?
Neutralization → solvent evaporation → extraction in dichlomethane → removing of the aqueous phase → drying with Na2SO4 → dichloromethane evaporation.
Salt formation:
Solution in an oxygen containing solvent (e.g. THF, ethanol , isopropanol, etc.) → saturation with gaseous HCl at oC, (ice bath ) up to acidic to litmus (open flask in the fume cupboard) → cupping and storing in the refrigerator, overnight → filtration.
If not equipped, try an organic acid.
But, where is the sodium comes from?
More
VOTE