Vilsmeier reaction

There should be no problem in the reaction process, is it not good to choose the lattice of the running board, the product raw material is not separated?

1. Do you not detect in your reaction?After treatment, the time is detected and wasting time.
2. Can consider increasing the reaction temperature.

The above forces, no chloroform, but the hydroxyl solution consumes Vilsmeier reagents, suggesting more POCL3

The hydroxyl group is not convinced, and the two hydroxyl groups are simultaneously chlorinated

The reaction can be heated, the solvent can be replaced with DCM or 1,2-dichloroethane, and the reaction to be added to the reaction, and the water is to participate in the reaction, if possible, it is recommended to protect the hydroxyl group.