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Meja Meja

Workup of Sandmeyer reaction?

David Miller  Follow
Quote from:
1). Before working in the lab, read carefully the Vogel’s Textbook of Practical Chemistry (e.g. 5th Edition)-Chapter: Reactions involving replacement of the diazo group (bromo-, dibromo-, tribromobenzene).
2). Work in the lab hood and shut the protective screen.
3). Wear protective eye-glasses.
4). The temperature must not exceed 0-5oC during nitrite addition and 10oC during the reaction, except if otherwise written in the Vogel's Textbook.
5). Keep a spare amount of ice for cooling until the end of the reaction; you may need it if the reaction gets vigorous.

Thank you for your response, but what I am asking is what happens after the reaction is complete - is my product supposed to precipitate in the solution?

I have read about the safety issues of diazo compounds, but I will continue to do so until I know everything about the reaction.

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Chamari B.S. Rajapaksha  Follow
1). Before working in the lab, read carefully the Vogel’s Textbook of Practical Chemistry (e.g. 5th Edition)-Chapter: Reactions involving replacement of the diazo group (bromo-, dibromo-, tribromobenzene).
2). Work in the lab hood and shut the protective screen.
3). Wear protective eye-glasses.
4). The temperature must not exceed 0-5oC during nitrite addition and 10oC during the reaction, except if otherwise written in the Vogel's Textbook.
5). Keep a spare amount of ice for cooling until the end of the reaction; you may need it if the reaction gets vigorous.

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Donald Emily  Follow
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Whether crystallizing or not, it depends on your molecule.
Anyway, if not crystallizing and being an oil, it can be separated by extractions with an organic solvent.

Ok, thank you! :)

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Dan Klein  Follow
Whether crystallizing or not, it depends on your molecule.
Anyway, if not crystallizing and being an oil, it can be separated by extractions with an organic solvent.

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