Home > Community > Does diarrhea affect the absorption of extended release medication? I took Vyvanse and had some diarrhea (once) about 3 hours later.
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Martha Stokes

Does diarrhea affect the absorption of extended release medication? I took Vyvanse and had some diarrhea (once) about 3 hours later.

Chris Bevis  Follow

Yes, increased gastric and intestinal motility can affect the duration of some medications because the coating that allows it to be released slowly doesn’t have the time to degrade and release as intended. Sometimes entire pills can be seen in the stool. If you have chronic diarrhea this is a consideration in the formulation of medication your healthcare provider will prescribe. But everyone experiences gastroenteritis at some point and this medication may provide the best effect overall.

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Anselmo  Follow

It can, depending on how it’s made — different technologies for different drugs.

Best idea is to discuss with a pharmacist.

Also, it’s a bit unusual to have one-time diarrhea. Does this happen often? Have you talked with your doctor about it? It would be helpful to know. It can be something like irritable bowel syndrome, which is controllable with dietary change.

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