Home > Community > Does exercise cause stimulants, such as Adderall and Vyvanse, to metabolise out of your system faster?
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Minhsan Nguyen

Does exercise cause stimulants, such as Adderall and Vyvanse, to metabolise out of your system faster?

Cammie Wait  Follow

About 50% of adderrall is metabolized in your liver. Exercise won’t change this.

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However, about 40% - 60% is excreted unchanged through the kidney.

When you do exercise, your body reduces the blood flow to the kidneys, to save up water for blood circulation and sweat-cooling.

When strenuous exercise is performed, kidney function can fall up to 25%.

So we can estimate that when you do intensive exercise, and only while it is happening, Adderall total elimination speed goes down up to 15%.

100% - (60% x 25%) = 85%

Sources:

1.- Product Information: ADDERALL XR(R) oral capsules, dextroamphetamine sulfate, dextroamphetamine saccharate, amphetamine aspartate monohydrate, amphetamine sulfate oral capsules. Shire US Inc, Wayne, PA, 2010.

2.-Poortmans JR. Exercise and renal function. Sports Med. 1984 Mar-Apr;1(2):125-53. doi: 10.2165/00007256-198401020-00003. PMID: 6567229.

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CheeHock Chew  Follow

About 50% of adderrall is metabolized in your liver. Exercise won’t change this.

However, about 40% - 60% is excreted unchanged through the kidney.

When you do exercise, your body reduces the blood flow to the kidneys, to save up water for blood circulation and sweat-cooling.

When strenuous exercise is performed, kidney function can fall up to 25%.

So we can estimate that when you do intensive exercise, and only while it is happening, Adderall total elimination speed goes down up to 15%.

100% - (60% x 25%) = 85%

Sources:

1.- Product Information: ADDERALL XR(R) oral capsules, dextroamphetamine sulfate, dextroamphetamine saccharate, amphetamine aspartate monohydrate, amphetamine sulfate oral capsules. Shire US Inc, Wayne, PA, 2010.

2.-Poortmans JR. Exercise and renal function. Sports Med. 1984 Mar-Apr;1(2):125-53. doi: 10.2165/00007256-198401020-00003. PMID: 6567229.

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