Home > Community > Hello all, what would be a best way to prepare Temozolomide(TMZ)...
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KENNETH ROTICH

Hello all, what would be a best way to prepare Temozolomide(TMZ)...

Bholu Friend  Follow

Great!!! Thanks

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Brad Moffat  Follow

Hi
I also have the same issue...
Did you find any solution?
Best

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Dave Calhoun  Follow

Dear Andrea Emanuelli ,
Yes, I found the solution by first dissolving the TMZ in DMSO and then later adding ddH2O slowly while still gently shaking it on the vortex. Further, I let it mix on the Eppendorf thermomixer maintaining between 25 to 30 degrees for few minutes, this gives me a clear solution. I prepared it fresh every time before proceeding with the oral gavage. Hope this helps.
Good luck

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