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How can I prepare a racemate of Henry reaction between...
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Aidan Cooney
How can I prepare a racemate of Henry reaction between...
The classic way is to form a nitronate and then add the aldehyde. Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group. http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
The classic way is to form a nitronate and then add the aldehyde. Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group. http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
Ugale, I would like to add --- Kopylovich, Maximilian N. et al, Chemistry - A European Journal, 19(2), 588-600; 2013. --- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012 --- Liu, Yu-Yu et al, Chinese Journal of Chemistry, 26(12), 2267-2272; 2008 --- Wang, Xiu et al, Tetrahedron Letters, 49(45), 6442-6444; 2008 --- Jammi, Suribabu et al, Chemistry - An Asian Journal, 4(2), 314-320; 2009 --- Kantam, M. Lakshmi et al, Advanced Synthesis & Catalysis, 348(4 + 5), 569-578; 2006 --- Veisi, Hojat et al, Tetrahedron Letters, 55(38), 5311-5314; 2014 --- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012 --- Phukan, Mridula et al, Green Chemistry Letters and Reviews, 2(4), 249-253; 2009 Good luck
Ugale, I would like to add --- Kopylovich, Maximilian N. et al, Chemistry - A European Journal, 19(2), 588-600; 2013. --- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012 --- Liu, Yu-Yu et al, Chinese Journal of Chemistry, 26(12), 2267-2272; 2008 --- Wang, Xiu et al, Tetrahedron Letters, 49(45), 6442-6444; 2008 --- Jammi, Suribabu et al, Chemistry - An Asian Journal, 4(2), 314-320; 2009 --- Kantam, M. Lakshmi et al, Advanced Synthesis & Catalysis, 348(4 + 5), 569-578; 2006 --- Veisi, Hojat et al, Tetrahedron Letters, 55(38), 5311-5314; 2014 --- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012 --- Phukan, Mridula et al, Green Chemistry Letters and Reviews, 2(4), 249-253; 2009 Good luck
The classic way is to form a nitronate and then add the aldehyde. Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group. http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
The classic way is to form a nitronate and then add the aldehyde. Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group. http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
The classic way is to form a nitronate and then add the aldehyde.
Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group.
http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
The classic way is to form a nitronate and then add the aldehyde.
Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group.
http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
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Ugale,
I would like to add
--- Kopylovich, Maximilian N. et al, Chemistry - A European Journal, 19(2), 588-600; 2013.
--- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012
--- Liu, Yu-Yu et al, Chinese Journal of Chemistry, 26(12), 2267-2272; 2008
--- Wang, Xiu et al, Tetrahedron Letters, 49(45), 6442-6444; 2008
--- Jammi, Suribabu et al, Chemistry - An Asian Journal, 4(2), 314-320; 2009
--- Kantam, M. Lakshmi et al, Advanced Synthesis & Catalysis, 348(4 + 5), 569-578; 2006
--- Veisi, Hojat et al, Tetrahedron Letters, 55(38), 5311-5314; 2014
--- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012
--- Phukan, Mridula et al, Green Chemistry Letters and Reviews, 2(4), 249-253; 2009
Good luck
Ugale,
I would like to add
--- Kopylovich, Maximilian N. et al, Chemistry - A European Journal, 19(2), 588-600; 2013.
--- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012
--- Liu, Yu-Yu et al, Chinese Journal of Chemistry, 26(12), 2267-2272; 2008
--- Wang, Xiu et al, Tetrahedron Letters, 49(45), 6442-6444; 2008
--- Jammi, Suribabu et al, Chemistry - An Asian Journal, 4(2), 314-320; 2009
--- Kantam, M. Lakshmi et al, Advanced Synthesis & Catalysis, 348(4 + 5), 569-578; 2006
--- Veisi, Hojat et al, Tetrahedron Letters, 55(38), 5311-5314; 2014
--- Uchida, Natsuko et al, Journal of Organic Chemistry, 77(23), 10631-10637; 2012
--- Phukan, Mridula et al, Green Chemistry Letters and Reviews, 2(4), 249-253; 2009
Good luck
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Ajay Jakhar , Can I get the procedure or the refrence for it ?
Ajay Jakhar , Can I get the procedure or the refrence for it ?
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The classic way is to form a nitronate and then add the aldehyde.
Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group.
http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
The classic way is to form a nitronate and then add the aldehyde.
Simply workup up the reaction by adding ammonium chloride instead of HCl and extract with EtOAc if you want the hydroxy nitro group.
http://orgsyn.org/Content/pdfs/procedures/CV1P0413.pdf
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You may read:
Frederick A. Luzzio, The Henry reaction: recent examples, Tetrahedron 57 (2001) 915-945.
You may read:
Frederick A. Luzzio, The Henry reaction: recent examples, Tetrahedron 57 (2001) 915-945.
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You can easily prepare racamic nitro aldol product by using triethylamine.
You can easily prepare racamic nitro aldol product by using triethylamine.
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